Z-Dap(Fmoc)-OH
Nα-Z-Nβ-Fmoc-L-2,3-diaminopropionic acid (CAS 142855-80-9), with the empirical formula C26H24N2O6 and a molecular weight of 460.48 g/mol, is a protected amino acid derivative. It is a key building block in peptide synthesis, particularly for incorporating unnatural amino acid residues into peptide chains. This compound is vital for research in chemical biology and synthesis.
- IUPAC
- Nα-Z-Nβ-Fmoc-L-2,3-diaminopropionic acid,Z-3-(Fmoc-amino)-L-alanine
- Synonyms
- Nα-Z-Nβ-Fmoc-L-2,3-diaminopropionic acidZ-3-(Fmoc-amino)-L-alanine

Peptide Synthesis
Utilised as a protected unnatural amino acid derivative for the synthesis of complex peptides and peptidomimetics. Its unique structure allows for the introduction of specific functionalities into peptide sequences.
Chemical Biology Research
Serves as a valuable tool in chemical biology for creating modified peptides that can be used to probe biological pathways or develop new therapeutic agents.
Organic Synthesis
Employed as a chiral building block in multi-step organic synthesis, enabling the construction of complex molecular architectures.
Unnatural Amino Acid Incorporation
Facilitates the incorporation of 2,3-diaminopropionic acid (DAP) derivatives into peptides, expanding the scope of achievable peptide structures and functions.
| Molecular weight | 460.48 |
|---|---|
| Empirical formula | C26H24N2O6 |
| Assay | ≥98.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-Dap(Fmoc)-OH used for?
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Z-Dap(Fmoc)-OH is primarily used in peptide synthesis as a protected unnatural amino acid derivative for incorporating 2,3-diaminopropionic acid residues. It is also a valuable tool in chemical biology and organic synthesis research.
What is the CAS number and formula for Z-Dap(Fmoc)-OH?
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The CAS number is 142855-80-9, and the empirical formula is C26H24N2O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Z-Dap(Fmoc)-OH with an assay of ≥98.0% (HPLC). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling considerations for Z-Dap(Fmoc)-OH?
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This compound has a WGK Germany rating of 3. Appropriate personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended for respiratory protection.
How is Z-Dap(Fmoc)-OH packed and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Products are carefully packed to ensure integrity during domestic and international shipment.
How can I request a sample or quote for Z-Dap(Fmoc)-OH?
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To request a sample or obtain a quote for Z-Dap(Fmoc)-OH, please contact our sales team via the website or direct inquiry, providing your specific requirements.
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