Uroguanylin
Uroguanylin (CAS: 154525-25-4), a peptide with the formula C64H102N18O26S4 and a molecular weight of 1667.86 g/mol, is a biologically active molecule primarily studied for its role in cell signalling. It functions as a guanylate cyclase activator, influencing cellular processes. This peptide is essential for researchers investigating gastrointestinal physiology, fluid secretion, and related signalling pathways.
- IUPAC
- Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu [Disulfide bridges: 4–12, 7–15]
Cell Signalling Research
Uroguanylin is utilised in research to investigate intracellular cyclic guanosine monophosphate (cGMP) production. It serves as a tool for understanding signal transduction pathways regulated by guanylate cyclase activation, particularly within the context of the gastrointestinal system.
Physiological Studies
Researchers employ Uroguanylin to study its physiological effects, including its influence on ion transport and fluid secretion in epithelial tissues. This is crucial for understanding normal gut function and the pathophysiology of related disorders.
Guanylate Cyclase Activation Studies
As a known activator of guanylate cyclase, Uroguanylin is used to characterise the enzyme's activity and to screen for potential modulators. Its specific action helps elucidate the downstream effects of cGMP signalling.
| Molecular weight | 1667.86 |
|---|---|
| Empirical formula | C64H102N18O26S4 |
| Assay | ≥90% (HPLC) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... GUCA2B(2981) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Uroguanylin used for?
+
Uroguanylin is primarily used in scientific research for studying cell signalling, particularly the activation of guanylate cyclase and the resulting downstream effects of cGMP. It is also employed in physiological studies investigating ion transport and fluid secretion in epithelial tissues.
What is the CAS number and formula for Uroguanylin?
+
The CAS number for Uroguanylin is 154525-25-4, and its empirical formula is C64H102N18O26S4.
What grade and purity does Tech Serve Solutions supply for Uroguanylin?
+
Tech Serve Solutions supplies Uroguanylin with an assay of ≥90% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
How should Uroguanylin be handled and stored?
+
Handling Uroguanylin requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The recommended storage temperature is −20°C.
How is Uroguanylin packed, shipped, and exported?
+
Uroguanylin is carefully packed to maintain its integrity during transit. As a specialist global supplier, Tech Serve Solutions handles the export of chemicals like Uroguanylin, adhering to all relevant international shipping regulations.
How can I request a quote or sample for Uroguanylin?
+
To request a quote or sample for Uroguanylin, please use the contact form on our website or reach out to our sales team directly with your specific requirements.
▶ Related products
(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology
(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis