Tris(2,4-dimethyl-5-sulfophenyl)phosphine trisodium salt
Tris(2,4-dimethyl-5-sulfophenyl)phosphine trisodium salt (CAS: 443150-11-6) is a phosphine ligand with the molecular formula ((C<sub>6</sub>H<sub>2</sub>)(CH<sub>3</sub>)<sub>2</sub>(SO<sub>3</sub>Na))<sub>3</sub>P and a molecular weight of 652.58 g/mol. This compound is primarily utilised as a catalyst in aqueous media for various cross-coupling reactions, offering an environmentally friendly alternative to traditional organic solvents. Its application extends to facilitating Heck, Sonogashira, and Suzuki couplings.
- IUPAC
- Benzenesulfonic acid, 3′, 3′′, 3′′′-phosphinidynetris[4,6-dimethyl-trisodium salt],TXPTS,Tris(4,6-dimethyl-3-sulfanatophenyl)phosphine trisodium salt
- Synonyms
- ((C6H2)(CH3)2(SO3Na))3PBenzenesulfonic acid, 3′, 3′′, 3′′′-phosphinidynetris[4,6-dimethyl-trisodium salt]TXPTSTris(4,6-dimethyl-3-sulfanatophenyl)phosphine trisodium salt
Catalysis in Aqueous Media
This phosphine ligand is specifically designed for use in water, enabling environmentally benign Heck, Sonogashira, and Suzuki cross-coupling reactions. It provides a viable route for sustainable synthesis by reducing reliance on volatile organic solvents.
Heck Coupling
Tris(2,4-dimethyl-5-sulfophenyl)phosphine trisodium salt acts as an effective ligand in the palladium-catalysed Heck reaction, facilitating the formation of carbon-carbon bonds between aryl or vinyl halides and alkenes in aqueous conditions.
Sonogashira Coupling
The compound serves as a crucial ligand in Sonogashira coupling reactions, enabling the formation of carbon-carbon bonds between terminal alkynes and aryl or vinyl halides, with applications in aqueous systems.
Suzuki Coupling
Utilised as a ligand in palladium-catalysed Suzuki-Miyaura coupling, this trisodium salt facilitates the reaction between organoboron compounds and organic halides, offering a water-soluble catalytic system.
| Molecular weight | 652.58 |
|---|---|
| Linear formula | ((C6H2)(CH3)2(SO3Na))3P |
| Assay | 95% |
| Application | Used for Heck, Sonogashira and Suzuki coupling in water |
| Melting point | >300 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What are the primary applications of Tris(2,4-dimethyl-5-sulfophenyl)phosphine trisodium salt?
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This compound is primarily used as a ligand in aqueous media for palladium-catalysed Heck, Sonogashira, and Suzuki cross-coupling reactions.
What is the CAS number and formula for Tris(2,4-dimethyl-5-sulfophenyl)phosphine trisodium salt?
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The CAS number is 443150-11-6 and the linear formula is ((C<sub>6</sub>H<sub>2</sub>)(CH<sub>3</sub>)<sub>2</sub>(SO<sub>3</sub>Na))<sub>3</sub>P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tris(2,4-dimethyl-5-sulfophenyl)phosphine trisodium salt with a purity of 95%. This product is not represented as USP, BP, EP, or other pharmacopoeia grades and is intended for research and laboratory use.
What are the safety and handling considerations for this chemical?
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This compound has a WGK Germany classification of 3, indicating it is hazardous to water. Always handle with appropriate personal protective equipment in a well-ventilated area, and consult the Safety Data Sheet (SDS) for detailed hazard information and handling procedures.
How is Tris(2,4-dimethyl-5-sulfophenyl)phosphine trisodium salt packed and shipped?
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Products are carefully packed according to international shipping regulations and are exported globally by Tech Serve Solutions. Specific packaging details will be provided with your quotation.
How can I request a quote or sample?
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To request a quote or a sample of Tris(2,4-dimethyl-5-sulfophenyl)phosphine trisodium salt, please contact our sales team through the website or direct email, referencing the CAS number 443150-11-6.
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