Tris(2,4-dimethylphenyl)phosphine
Tris(2,4-dimethylphenyl)phosphine (CAS 49676-42-8), with a molecular formula of C24H27P and a molecular weight of 346.44, is a specialised phosphine compound. It is primarily utilised as a reactant in sulfonylation reactions, a catalyst for the curing of epoxy resins, and as a ligand precatalyst in Heck coupling reactions. This compound is supplied by TSS with a high purity of 97%.
- IUPAC
- Tri-2,4-xylylphosphine
- Synonyms
- Tri-2,4-xylylphosphine

Reactant for Sulfonylation Reactions
Tris(2,4-dimethylphenyl)phosphine serves as a valuable reactant in the synthesis of sulfonated organic compounds. Its specific structure facilitates controlled sulfonylation processes in chemical synthesis.
Catalyst for Epoxy Resin Curing
This phosphine compound acts as an effective catalyst for the curing of epoxy resins. It plays a role in initiating or accelerating the polymerisation process, leading to the formation of cross-linked polymer networks.
Ligand Precatalyst for Heck Coupling
In the realm of palladium-catalysed cross-coupling, Tris(2,4-dimethylphenyl)phosphine functions as a ligand precatalyst. It is integral to facilitating Heck coupling reactions, enabling the formation of carbon-carbon bonds.
| Molecular weight | 346.44 |
|---|---|
| Empirical formula | C24H27P |
| Assay | 97% |
| Application | Reactant for sulfonylation reactions1Catalyst for epoxy resin curing2Ligand precatalyst for Heck coupling3 |
| Melting point | 158-162 °C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 1 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What are the main applications of Tris(2,4-dimethylphenyl)phosphine?
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Tris(2,4-dimethylphenyl)phosphine is used as a reactant for sulfonylation reactions, a catalyst for epoxy resin curing, and as a ligand precatalyst for Heck coupling reactions.
What is the CAS number and molecular formula for Tris(2,4-dimethylphenyl)phosphine?
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The CAS number is 49676-42-8, and the molecular formula is C24H27P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tris(2,4-dimethylphenyl)phosphine with an assay of 97%. This product is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should Tris(2,4-dimethylphenyl)phosphine be handled?
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Tris(2,4-dimethylphenyl)phosphine is a Warning substance classified with H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection in a well-ventilated area. In case of contact, follow precautionary statements P261 and P305 + P351 + P338.
Is Tris(2,4-dimethylphenyl)phosphine a controlled substance?
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The provided data does not indicate that Tris(2,4-dimethylphenyl)phosphine is a controlled substance.
How is this chemical packed and exported?
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Tech Serve Solutions, as a global supplier and exporter, ensures appropriate packaging for international shipment of chemicals like Tris(2,4-dimethylphenyl)phosphine, adhering to all relevant regulations.
How can I request a sample or quote for Tris(2,4-dimethylphenyl)phosphine?
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To request a sample or quote for Tris(2,4-dimethylphenyl)phosphine, please contact the TSS sales department through our website or directly via email/phone.
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