Tris(2-ethylhexyl)phosphine oxide
Tris(2-ethylhexyl)phosphine oxide (CAS: 2785-32-2) is an organophosphorus compound with the formula C24H51OP and a molecular weight of 386.63 g/mol. This high-purity Selectophore™ grade chemical functions as a crucial solvent mediator, particularly in the development of potentiometric serotonin selective electrodes. Its specific properties make it valuable in analytical chemistry and sensor technology.
- IUPAC
- 3-[Bis(2-ethylhexyl)phosphorylmethyl]heptane

Serotonin Selective Electrode Mediator
Tris(2-ethylhexyl)phosphine oxide is employed as a solvent mediator in the fabrication of potentiometric electrodes designed for the selective detection of serotonin. This application leverages its ability to facilitate ion transport and improve electrode performance in electrochemical sensing.
Ion Sensor Development
This phosphine oxide derivative is utilised in the development of various ion-selective electrodes (ISEs). Its compatibility with membrane materials allows for the creation of sensitive and selective sensors for specific analytes in chemical analysis.
Chemical Synthesis
As a phosphine compound, it can serve as a building block or reagent in specialised organic synthesis pathways. Its unique structure may offer advantages in certain catalytic or ligand applications within inorganic and organometallic chemistry.
| Molecular weight | 386.63 |
|---|---|
| Empirical formula | C24H51OP |
| Assay | ≥95.0% (GC)≥95.0% |
| Grade | Selectophore™ |
| Refractive index | n20/D 1.467 |
| Storage temperature | 2-8°C |
| Application | Solvent mediator for serotonin selective electrodes |

Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tris(2-ethylhexyl)phosphine oxide used for?
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Tris(2-ethylhexyl)phosphine oxide (CAS: 2785-32-2) is primarily used as a solvent mediator for potentiometric serotonin selective electrodes and in the development of other ion-selective sensors. It also finds applications in chemical synthesis and as a phosphine ligand.
What are the CAS number and chemical formula for Tris(2-ethylhexyl)phosphine oxide?
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The CAS number is 2785-32-2, and the chemical formula is C24H51OP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tris(2-ethylhexyl)phosphine oxide in Selectophore™ grade with an assay of ≥95.0% (GC). We do not represent this product as meeting USP, BP, or EP pharmacopoeial standards.
How should Tris(2-ethylhexyl)phosphine oxide be handled safely?
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Tris(2-ethylhexyl)phosphine oxide is a hazardous substance that causes skin irritation (H315) and serious eye damage (H318). Appropriate personal protective equipment, including eyeshields and gloves, must be worn. Handle only in well-ventilated areas and consult the Safety Data Sheet for full protective measures. Storage is recommended at 2-8°C.
Is Tris(2-ethylhexyl)phosphine oxide a controlled substance?
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The provided data does not indicate that Tris(2-ethylhexyl)phosphine oxide is a controlled substance.
How is Tris(2-ethylhexyl)phosphine oxide packed and shipped?
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Tris(2-ethylhexyl)phosphine oxide is carefully packed for secure transit and exported globally by Tech Serve Solutions in compliance with all relevant shipping regulations.
How can I request a sample or quote for Tris(2-ethylhexyl)phosphine oxide?
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To request a sample or obtain a quotation for Tris(2-ethylhexyl)phosphine oxide, please contact our sales department via the website or email, providing your specific requirements.
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