Tris(2-pyridylmethyl)amine
Tris(2-pyridylmethyl)amine (CAS 16858-01-8, C18H18N4) is a chemical compound with a molecular weight of 290.36 g/mol. This versatile organic molecule serves as a crucial ligand in Atom Transfer Radical Polymerization (ATRP). Its specific structure enables precise control over polymerisation processes, facilitating the synthesis of advanced polymeric materials with defined architectures.
- IUPAC
- TPA,TPMA,Tri-(2-picolyl)amine,Tripicolylamine
- Synonyms
- TPMATripicolylamineTPATris(2-picolyl)amine

Atom Transfer Radical Polymerization (ATRP)
Tris(2-pyridylmethyl)amine functions as an effective ligand in ATRP, a controlled polymerisation technique. It forms active complexes with transition metal catalysts, enabling controlled chain growth and the synthesis of polymers with predictable molecular weights and low polydispersity.
Synthesis of Telechelic Polymers
This compound is utilised for creating telechelic polymers, which possess reactive end groups on both polymer chains. These functionalised polymers are valuable precursors for block copolymers and advanced material applications.
Catalysis
As a tridentate amine ligand, Tris(2-pyridylmethyl)amine can coordinate with various metal centres, finding use in diverse catalytic applications beyond ATRP, particularly in coordination chemistry and organometallic catalysis.
| Molecular weight | 290.36 |
|---|---|
| Empirical formula | C18H18N4 |
| Assay | 98% |
| Form | solid |
| Application | Atom Transfer Radical Polymerization (ATRP) ligand for the creation of telechelic polymers.1,2,3,4 |
| Melting point | 85-89 °C |

Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 1 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tris(2-pyridylmethyl)amine used for?
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Tris(2-pyridylmethyl)amine is primarily used as a ligand in Atom Transfer Radical Polymerization (ATRP) for controlled polymer synthesis and the creation of telechelic polymers. It also finds applications in catalysis.
What are the CAS number and formula for Tris(2-pyridylmethyl)amine?
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The CAS number for Tris(2-pyridylmethyl)amine is 16858-01-8, and its molecular formula is C18H18N4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tris(2-pyridylmethyl)amine with a minimum assay of 98%. This product is intended for research and laboratory use; it is not supplied as USP, BP, EP, or pharmaceutical grade.
How should Tris(2-pyridylmethyl)amine be handled safely?
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Tris(2-pyridylmethyl)amine is classified as harmful if swallowed (H302). Handle with appropriate personal protective equipment, including gloves and eye protection, and avoid ingestion. Consult the Safety Data Sheet (SDS) for detailed handling information.
Is Tris(2-pyridylmethyl)amine available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Tris(2-pyridylmethyl)amine, and can arrange shipment worldwide.
How can I request a quote or sample?
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To request a quote or sample of Tris(2-pyridylmethyl)amine, please contact our sales team through the website or by phone, providing your specific requirements.
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