Tris(2,4,6-trimethylphenyl)phosphine
Tris(2,4,6-trimethylphenyl)phosphine (CAS: 23897-15-6) is a sterically hindered phosphine ligand with a molecular weight of 388.52 g/mol. Its bulky mesityl groups provide unique electronic and steric properties, making it valuable in homogeneous catalysis. It is commonly employed in cross-coupling reactions and other organometallic transformations where precise control over the coordination sphere of a metal centre is required. Supplied by TSS at 97% purity.
- IUPAC
- Trimesitylphosphine
- Synonyms
- 23897-15-6, [(CH3)3C6H2]3P, Trimesitylphosphine
![Tris(2,4,6-trimethylphenyl)phosphine ([(CH3)3C6H2]3P) — chemical structure, CAS 23897-15-6; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F23897-15-6.png&w=3840&q=75)
Homogeneous Catalysis
Tris(2,4,6-trimethylphenyl)phosphine serves as a crucial ligand in various homogeneous catalytic systems. Its bulky nature influences catalyst activity and selectivity, particularly in palladium-catalyzed cross-coupling reactions.
Organometallic Chemistry
This phosphine is used to stabilise low-coordinate metal centres and modulate their reactivity. It is a common component in the synthesis of complex organometallic compounds for research and development.
Cross-Coupling Reactions
The steric bulk of trimesitylphosphine makes it highly effective in promoting challenging cross-coupling reactions such as Suzuki, Buchwald-Hartwig, and Sonogashira couplings, often leading to improved yields and reduced side products.
Chemical Synthesis
As a versatile building block and ligand, it facilitates diverse synthetic transformations in organic and inorganic chemistry, enabling the construction of intricate molecular architectures.
| Molecular weight | 388.52 |
|---|---|
| Linear formula | [(CH3)3C6H2]3P |
| Assay | 97% |
| Melting point | 185-188 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tris(2,4,6-trimethylphenyl)phosphine used for?
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Tris(2,4,6-trimethylphenyl)phosphine is primarily used as a sterically hindered phosphine ligand in homogeneous catalysis, particularly in cross-coupling reactions and organometallic chemistry to influence catalyst performance and selectivity.
What is the CAS number and formula for Tris(2,4,6-trimethylphenyl)phosphine?
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The CAS number is 23897-15-6, and the linear formula is [(CH3)3C6H2]3P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tris(2,4,6-trimethylphenyl)phosphine at a purity of 97%. This is a technical/research grade, and TSS does not represent it as USP, BP, or EP.
How should Tris(2,4,6-trimethylphenyl)phosphine be handled safely?
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Handling requires appropriate personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Consult the Safety Data Sheet for full details on hazards and precautions.
Is Tris(2,4,6-trimethylphenyl)phosphine a controlled substance?
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The provided data does not indicate that Tris(2,4,6-trimethylphenyl)phosphine is a controlled substance.
How is Tris(2,4,6-trimethylphenyl)phosphine packed and shipped?
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TSS carefully packs and exports chemicals globally, adhering to all necessary regulations for safe transport and handling.
How can I request a sample or quote for Tris(2,4,6-trimethylphenyl)phosphine?
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To request a sample or a quote, please contact the TSS sales team through our website or by phone.
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