Trimethylsilyl 2,2-difluoro-2-(fluorosulfonyl)acetate
Trimethylsilyl 2,2-difluoro-2-(fluorosulfonyl)acetate (CAS: 120801-75-4) is a specialised organosilicon compound. With a molecular weight of 250.27 g/mol, it serves as a valuable fluoroalkylation agent. This chemical is primarily employed as a reactant in the synthesis of complex fluorinated organic molecules, including difluorocyclopropenes and difluorocarbene reagents. Its unique structure makes it a useful tool for introducing difluoromethylene groups in organic synthesis.
- IUPAC
- Trimethylsilyl (fluorosulfonyl)difluoroacetate
- Synonyms
- FSO2CF2CO2Si(CH3)3Trimethylsilyl (fluorosulfonyl)difluoroacetate
Fluoroalkylation Agent
This compound acts as an effective agent for introducing fluoroalkyl groups, specifically the difluoromethylene group, into organic molecules. This is crucial for modifying the properties of target compounds in pharmaceutical and materials science research.
Synthesis of Difluorocyclopropenes
Trimethylsilyl 2,2-difluoro-2-(fluorosulfonyl)acetate is a key reactant in the preparation of difluorocyclopropene derivatives. These cyclic compounds are of interest in organic synthesis for further transformations.
Precursor to Difluorocarbene Reagents
It serves as a precursor for generating difluorocarbene reagents in situ. Difluorocarbene is a highly reactive intermediate used in various cycloaddition and insertion reactions.
| Molecular weight | 250.27 |
|---|---|
| Linear formula | FSO2CF2CO2Si(CH3)3 |
| Boiling point | 156 °C(lit.) |
| Density | 1.27 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.367(lit.) |
| Application | • Fluoroalkylation agent1Reactant for:• Preparation of difluorocyclopropenes2• Preparation of difluorocarbene reagents3 |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | 26 °C / 78.8 °F |
|---|---|
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trimethylsilyl 2,2-difluoro-2-(fluorosulfonyl)acetate used for?
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It is primarily used as a fluoroalkylation agent and a reactant in the preparation of difluorocyclopropenes and difluorocarbene reagents.
What is the CAS number and formula for Trimethylsilyl 2,2-difluoro-2-(fluorosulfonyl)acetate?
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The CAS number is 120801-75-4, and its linear formula is FSO2CF2CO2Si(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical typically as a research or technical grade material. We do not represent it as USP, BP, or EP grade unless explicitly stated otherwise. Please refer to the product's Certificate of Analysis for specific purity details.
What are the safety and handling precautions for this chemical?
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This substance is classified as Danger (GHS02, GHS05) with hazards H226 (Flammable liquid and vapour) and H314 (Causes severe skin burns and eye damage). Handle with appropriate personal protective equipment, including gloves, eye protection, and protective clothing, in a well-ventilated area. Avoid ignition sources.
How is this chemical packed, shipped, and exported?
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This chemical is classified as UN 2920, Packing Group II, for transport. Tech Serve Solutions adheres to all international regulations for the safe packing, shipping, and export of hazardous chemicals.
How can I request a sample or quote?
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Please contact our sales team directly through the website or by phone to request a sample or a formal quotation for Trimethylsilyl 2,2-difluoro-2-(fluorosulfonyl)acetate.
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