Neostigmine bromide
Neostigmine bromide (CAS: 114-80-7, Formula: C12H19BrN2O2) is a quaternary ammonium compound with a molecular weight of 303.20. It functions as a reversible acetylcholinesterase inhibitor. This white powder is primarily utilised in biochemical research and as a reagent in analytical applications, particularly within neuroscience and cell biology research settings. Its specific inhibitory action on cholinesterase enzymes makes it a valuable tool for studying neurotransmission.
- IUPAC
- 3-(N,N-Dimethylcarbamoyloxy)-N,N,N,-trimethylanilinium bromide,Prostigmine
- Synonyms
- 3-(N,N-Dimethylcarbamoyloxy)-N,N,N,-trimethylanilinium bromideProstigmine
Cholinesterase Inhibition Research
Neostigmine bromide serves as a key reagent for studying the function and inhibition of acetylcholinesterase (ACHE) enzymes in research settings. It is valuable for investigating neurotransmission and its modulation.
Neuroscience and Cell Biology Reagent
This compound is employed as a research tool in neuroscience and cell biology. It aids in understanding cellular signaling pathways and neurobiological processes that involve cholinergic systems.
Analytical Applications
Utilised in specific analytical methods, Neostigmine bromide can be applied in the detection or characterisation of cholinesterase activity. Its predictable inhibitory action supports precise experimental designs.
| Molecular weight | 303.20 |
|---|---|
| Empirical formula | C12H19BrN2O2 |
| Assay | ≥98% (HPLC and titration) |
| Form | powder |
| Colour | white |
| Solubility | H2O: soluble1 g/mLethanol: soluble |
| Melting point | 175-177 °C(lit.) |
Hazard statements
- H300Fatal if swallowed
- H310Fatal in contact with skin
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H330Fatal if inhaled
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P302IF ON SKIN
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28-36/37/38-42/43 |
| Safety statements (S) | 22-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ACHE(43) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Neostigmine bromide used for?
+
Neostigmine bromide is used in biochemical research as a reversible acetylcholinesterase inhibitor, particularly in studies related to neuroscience and cell biology, and in certain analytical applications.
What is the CAS number and chemical formula for Neostigmine bromide?
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The CAS number for Neostigmine bromide is 114-80-7, and its chemical formula is C12H19BrN2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Neostigmine bromide with an assay of ≥98% (HPLC and titration). We do not represent this product as USP, BP, or EP grade.
How should Neostigmine bromide be handled safely?
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Neostigmine bromide is classified as Danger, with hazards including acute toxicity (oral, dermal, inhalation) and skin/eye irritation. Handling requires appropriate personal protective equipment such as eyeshields, face shields, gloves, and P2 respirator cartridges. Always consult the Safety Data Sheet for full details.
Is Neostigmine bromide a controlled substance?
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The provided data does not indicate that Neostigmine bromide is a controlled substance.
How is Neostigmine bromide packed, shipped, and exported?
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Neostigmine bromide is supplied as a white powder. Shipping and export follow international regulations for hazardous materials, including UN 2811 classification.
How can I request a sample or quote for Neostigmine bromide?
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To request a sample or quote, please contact the TSS sales team via our website or direct contact details, specifying the required quantity and delivery location.
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