Neostigmine methyl sulfate
Neostigmine methyl sulfate (CAS 51-60-5), with the molecular formula C13H22N2O6S and a molecular weight of 334.39 g/mol, is a crucial acetylcholinesterase inhibitor. It is primarily recognised for its role in clinical applications, particularly in managing conditions related to neuromuscular transmission. This compound is vital in research settings for studying cholinergic systems and developing new therapeutic strategies. Tech Serve Solutions supplies this important chemical intermediate.
- IUPAC
- 3-(N,N-Dimethylcarbamoyloxy)-N,N,N,-trimethylanilinium methyl sulfate
Neuromuscular Function Studies
Neostigmine methyl sulfate is extensively used in research to investigate the mechanisms of neuromuscular transmission. It serves as a tool for understanding the function of acetylcholine receptors and acetylcholinesterase enzymes in physiological and pathological states.
Pharmacological Research
This compound is employed in drug discovery and development programs focused on cholinergic pathways. Its properties as an acetylcholinesterase inhibitor make it valuable for screening potential new therapeutic agents targeting neurological disorders.
Biochemical Assays
Neostigmine methyl sulfate can be utilized in biochemical assays to quantify acetylcholinesterase activity or to study enzyme kinetics. It provides a reliable method for assessing enzyme inhibition and substrate interaction.
| Molecular weight | 334.39 |
|---|---|
| Empirical formula | C13H22N2O6S |
| Storage temperature | −20°C |
Hazard statements
- H300Fatal if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P301IF SWALLOWED
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 28-36/37/38-42/43 |
| Safety statements (S) | 36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Neostigmine methyl sulfate used for?
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Neostigmine methyl sulfate is primarily used in research for studying neuromuscular function, pharmacological research related to cholinergic pathways, and in biochemical assays to measure acetylcholinesterase activity.
What are the CAS number and formula for Neostigmine methyl sulfate?
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The CAS number for Neostigmine methyl sulfate is 51-60-5, and its molecular formula is C13H22N2O6S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Neostigmine methyl sulfate suitable for research and development purposes. Specific purity and assay details are available upon request; we do not represent this product as USP, BP, or EP grade.
How should Neostigmine methyl sulfate be handled?
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Neostigmine methyl sulfate is a dangerous substance requiring strict handling precautions. It is acutely toxic if swallowed and causes skin and eye irritation. Inhalation can cause respiratory irritation and allergic reactions. Always use appropriate personal protective equipment, including eyeshields, gloves, and a respirator, and handle in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for detailed information.
Is Neostigmine methyl sulfate a controlled substance?
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The provided data does not indicate that Neostigmine methyl sulfate is a controlled substance under standard chemical regulations. However, users should always verify local and international regulations regarding its handling and use.
How is Neostigmine methyl sulfate packed and shipped?
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Neostigmine methyl sulfate is packed according to UN 2811 specifications for hazardous materials, class 6.1, Packing Group II. Shipping and export are handled by Tech Serve Solutions in compliance with all relevant transportation regulations.
How can I request a sample or quote for Neostigmine methyl sulfate?
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To request a sample or a quote for Neostigmine methyl sulfate, please contact our sales department through the website or via email, providing your specific requirements and contact details.
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