2-Chloro-6-fluorobenzaldehyde
2-Chloro-6-fluorobenzaldehyde (CAS: 387-45-1) is a halogenated aromatic aldehyde with the molecular formula ClC6H3(F)CHO and a molecular weight of 158.56 g/mol. Supplied by Tech Serve Solutions at a minimum assay of 95%, this compound serves as a valuable building block in organic synthesis. Its structure, featuring both chlorine and fluorine substituents on the benzaldehyde core, makes it useful for introducing specific functionalities into more complex molecules, particularly in the fields of materials science and pharmaceutical research.

Synthesis of Novel Copolymers
2-Chloro-6-fluorobenzaldehyde has been utilised in the preparation of novel copolymers. Specifically, it was employed in the synthesis of copolymers of methyl 2-cyano-3-dihalophenyl-2-propenoates and styrene, demonstrating its utility in polymer chemistry.
Fluorinated Building Block
As a fluorinated organic building block, this compound is instrumental in the synthesis of advanced materials and pharmaceutical intermediates where the incorporation of fluorine atoms is desired to modulate properties such as lipophilicity, metabolic stability, or binding affinity.
Aryl Halide Chemistry
The presence of both chlorine and fluorine on the aromatic ring offers distinct reactivity for various chemical transformations. This allows for selective functionalisation, making it a versatile reagent in complex organic synthesis pathways.
| Molecular weight | 158.56 |
|---|---|
| Linear formula | ClC6H3(F)CHO |
| Assay | 95% |
| Application | 2-Chloro-6-fluorobenzaldehyde was used in the synthesis of novel copolymers of methyl 2-cyano-3-dihalophenyl-2-propenoates and styrene1. |
| Melting point | 32-35 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 102 °C / 215.6 °F |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-6-fluorobenzaldehyde used for?
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2-Chloro-6-fluorobenzaldehyde is primarily used as a building block in organic synthesis for creating more complex molecules, including novel copolymers and fluorinated compounds for materials science and pharmaceutical research.
What are the CAS number and molecular formula for 2-Chloro-6-fluorobenzaldehyde?
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The CAS number for 2-Chloro-6-fluorobenzaldehyde is 387-45-1, and its molecular formula is ClC6H3(F)CHO.
What grade and purity does Tech Serve Solutions supply for 2-Chloro-6-fluorobenzaldehyde?
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Tech Serve Solutions supplies 2-Chloro-6-fluorobenzaldehyde with a minimum assay of 95%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
What are the main safety hazards associated with 2-Chloro-6-fluorobenzaldehyde?
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2-Chloro-6-fluorobenzaldehyde is classified with the GHS07 symbol and carries a Warning signal word. It is hazardous and can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves should be used.
Is 2-Chloro-6-fluorobenzaldehyde available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Chloro-6-fluorobenzaldehyde. Please contact us for export details.
How can I request a sample or quote for 2-Chloro-6-fluorobenzaldehyde?
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To request a sample or a quotation for 2-Chloro-6-fluorobenzaldehyde, please use the contact form on our website or contact our sales department directly.
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