2-Chloro-6-fluoro-5-methylphenylboronic acid
2-Chloro-6-fluoro-5-methylphenylboronic acid (CAS: 352535-86-5) is an organoboron compound with the chemical formula ClC6H2(F)(CH3)B(OH)2. It has a molecular weight of 188.39 g/mol. This compound is primarily utilised as a building block in organic synthesis, particularly in cross-coupling reactions. Its specific substitution pattern makes it valuable for introducing complex aryl motifs into target molecules within research and development settings.
Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of complex organic molecules. Its structure is well-suited for Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds.
Pharmaceutical Research
Utilised in the discovery and development of new pharmaceutical agents. The unique halogen and methyl substitution can influence the biological activity of derived compounds.
Materials Science
Can be incorporated into novel materials through its reactive boronic acid moiety. This allows for the development of functional materials with tailored electronic or optical properties.
| Molecular weight | 188.39 |
|---|---|
| Linear formula | ClC6H2(F)(CH3)B(OH)2 |
| Melting point | 127-132 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-6-fluoro-5-methylphenylboronic acid used for?
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2-Chloro-6-fluoro-5-methylphenylboronic acid is primarily used as an intermediate in organic synthesis, especially for cross-coupling reactions like the Suzuki-Miyaura coupling, and in pharmaceutical and materials science research.
What are the CAS number and chemical formula for this compound?
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The CAS number is 352535-86-5, and the chemical formula is ClC6H2(F)(CH3)B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and development purposes. The specific grade and purity are available upon request and are not represented as USP, BP, EP, or any other pharmacopoeial standard.
What are the safety and handling considerations for 2-Chloro-6-fluoro-5-methylphenylboronic acid?
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This compound requires careful handling. Recommended personal protective equipment includes eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It is classified with WGK Germany 3, indicating a high hazard to water.
How is 2-Chloro-6-fluoro-5-methylphenylboronic acid packed and shipped?
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Tech Serve Solutions packs and ships fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all necessary safety and export regulations.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales team via the website or direct inquiry, providing the product name and CAS number.
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