Triisobutylphosphine
Triisobutylphosphine (CAS: 4125-25-1) is an organophosphorus compound with the linear formula [(CH3)2CHCH2]3P and a molecular weight of 202.32 g/mol. It serves as a versatile ligand in catalysis, particularly in transition metal-mediated organic synthesis. Its phosphine structure makes it valuable for reactions requiring electron-rich ligands. This compound is essential in various chemical synthesis applications where precise control over reaction pathways is required.
- IUPAC
- Cytop® 341,Tris(2-methylpropyl)phosphine
- Synonyms
- Tris(2-methylpropyl)phosphine
![Triisobutylphosphine ([(CH3)2CHCH2]3P) — chemical structure, CAS 4125-25-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F4125-25-1.png&w=3840&q=75)
Catalysis
Triisobutylphosphine acts as a ligand in homogeneous catalysis, facilitating transition metal-catalyzed reactions such as cross-couplings and hydroformylations. Its electron-donating properties can tune catalyst activity and selectivity.
Organic Synthesis
It is employed as a reagent or catalyst component in various organic transformations, contributing to the synthesis of complex molecules. Its use is critical in reactions where specific phosphine coordination is beneficial.
Ligand Chemistry
As a bulky, electron-rich phosphine ligand, it is used in coordination chemistry to stabilize low-valent metal complexes and study their reactivity.
| Molecular weight | 202.32 |
|---|---|
| Linear formula | [(CH3)2CHCH2]3P |
| Assay | ≥90% (GC) |
| Boiling point | 126 °C/50 mmHg(lit.) |
| Density | 0.811 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.451(lit.) |
Hazard statements
- H225Highly flammable liquid and vapour
- H250Catches fire spontaneously if exposed to air
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P222Do not allow contact with air
- P231Handle under inert gas
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P422
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 10 °C / 50 °F |
| Transport (UN / ADR) | UN 2845 4.2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 17-20/21/22-34 |
| Safety statements (S) | 16-23-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Triisobutylphosphine used for?
+
Triisobutylphosphine is primarily used as a ligand in catalysis, particularly in transition metal-mediated organic synthesis, and in coordination chemistry.
What are the CAS number and formula for Triisobutylphosphine?
+
The CAS number for Triisobutylphosphine is 4125-25-1. Its linear formula is [(CH3)2CHCH2]3P.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Triisobutylphosphine with an assay of ≥90% (GC). We do not represent this product as USP, BP, or EP grade.
How should Triisobutylphosphine be handled safely?
+
Triisobutylphosphine is a highly flammable liquid and vapour, causes severe skin burns and eye damage, and is harmful if inhaled, swallowed, or in contact with skin. Handle with extreme caution, using appropriate personal protective equipment including gloves, eye protection, and respiratory protection in a well-ventilated area.
How is Triisobutylphosphine packed and shipped?
+
Triisobutylphosphine is typically packed in accordance with UN 2845 regulations for hazardous materials, suitable for international export. Specific packaging details will be confirmed at the time of order.
How can I request a quote or sample for Triisobutylphosphine?
+
To request a quote or sample of Triisobutylphosphine, please contact our sales team through the website or by phone, providing your specific requirements.
▶ Related products
Benzeneruthenium(II) chloride dimer
Ru2(C6H6)2Cl4
Catalysis & Inorganic
Benzoylferrocene
C17H14FeO
Catalysis & Inorganic
Benzyldiphenylphosphine
C6H5CH2P(C6H5)2
Catalysis & Inorganic
Beryllium
Be
Catalysis & Inorganic
Beryllium oxide
BeO
Catalysis & Inorganic![Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer — chemical structure, CAS 12257-42-0; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F12257-42-0.png&w=3840&q=75)
Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer
Catalysis & Inorganic
![Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo — chemical structure, CAS 1228149-03-8; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1228149-03-8.png&w=3840&q=75)
Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo
1-d:1′
Catalysis & Inorganic![Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride (C16H20ClN3Ni) — chemical structure, CAS 1033772-47-2; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1033772-47-2.png&w=3840&q=75)
Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride
C16H20ClN3Ni
Catalysis & Inorganic▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis