Methyl chloroformate
Methyl chloroformate (CAS: 79-22-1), with the linear formula ClCOOCH₃ and a molecular weight of 94.50 g/mol, is a reactive organic compound. It is a clear, colourless liquid with a pungent odour. This chemical serves as a vital building block and reagent in organic synthesis, particularly for introducing the methoxycarbonyl group. Its applications span various chemical processes, including pharmaceutical intermediate production and laboratory research.
- IUPAC
- Chloroformic acid methyl ester
- Synonyms
- Chloroformic acid methyl esterMethyl chlorocarbonateMethyl oxycarbonyl chloride
Organic Synthesis Intermediate
Methyl chloroformate is extensively used as a methoxycarbonylating agent in the synthesis of pharmaceuticals and agrochemicals. It facilitates the introduction of the -COOCH₃ functional group into various organic molecules.
Reagent for Derivatization
It acts as a derivatization reagent, particularly in analytical chemistry, for preparing derivatives of alcohols and phenols. This aids in their detection and analysis, for example, in HPLC applications.
Building Block in Chemical Research
As a versatile building block, it is employed in academic and industrial research for the development of novel organic compounds and complex molecular structures.
| Molecular weight | 94.50 |
|---|---|
| Linear formula | ClCOOCH3 |
| Assay | 99% |
| Boiling point | 70-72 °C(lit.) |
| Density | 1.223 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.387(lit.) |
| Vapour pressure | 4.8 psi (20 °C) |
| Vapour density | 3.26 (vs air) |
| Autoignition temp | 905 °F |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H330Fatal if inhaled
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | 10 °C / 50 °F |
|---|---|
| Transport (UN / ADR) | UN 1238 6.1/PG 1 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F,T+ |
| Risk statements (R) | 11-21/22-26-34 |
| Safety statements (S) | 14-26-28-36/37/39-45-46-63 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl chloroformate used for?
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Methyl chloroformate is primarily used as an intermediate and building block in organic synthesis, notably for methoxycarbonylation reactions, and as a derivatization reagent in analytical chemistry.
What is the CAS number and formula for Methyl chloroformate?
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The CAS number for Methyl chloroformate is 79-22-1, and its linear formula is ClCOOCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl chloroformate with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should Methyl chloroformate be handled safely?
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Methyl chloroformate is a dangerous substance (Danger). It is highly flammable (H225), harmful if swallowed or inhaled (H302, H330), harmful in contact with skin (H312), and causes severe skin burns and eye damage (H314). Handle with extreme caution in a well-ventilated area, using appropriate personal protective equipment, and avoiding ignition sources.
How is Methyl chloroformate packed and shipped?
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Methyl chloroformate is packed and shipped according to stringent international regulations for hazardous materials, including UN 1238 classification. We export globally, ensuring compliance with all relevant transport and customs requirements.
How can I request a sample or quote for Methyl chloroformate?
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To request a sample or a quote for Methyl chloroformate, please contact our sales team through the website or by phone. Please provide your contact details and the quantity required.
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