Methyl chlorothiolformate
Methyl chlorothiolformate (CAS: 18369-83-0), with the linear formula ClCOSCH3 and a molecular weight of 110.56 g/mol, is a versatile organic building block. This sulfur-containing thiocarbonyl compound is primarily employed in chemical synthesis for introducing the methylthiocarbonyl group. Its reactivity makes it a valuable intermediate in the preparation of various organic molecules. Tech Serve Solutions supplies this chemical for research and development purposes.
Organic Synthesis Intermediate
Methyl chlorothiolformate serves as a key intermediate in organic synthesis, enabling the formation of new carbon-sulfur and carbon-heteroatom bonds. Its utility lies in the introduction of the CH3SC(O)- moiety into diverse molecular structures.
Building Block for Heterocycles
This compound can be utilised in the construction of heterocyclic ring systems, which are prevalent in pharmaceuticals and agrochemicals. Its specific functional groups allow for targeted cyclisation reactions.
Reagent in Thioester Formation
It acts as a direct precursor for the synthesis of methyl thioesters, important functional groups found in numerous biologically active compounds and used in various synthetic methodologies.
| Molecular weight | 110.56 |
|---|---|
| Linear formula | ClCOSCH3 |
| Assay | 96% |
| Boiling point | 110 °C(lit.) |
| Density | 1.288 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.49(lit.) |
| Storage temperature | 2-8°C |
| Impurities tested | ~4% dimethyl disulfide |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
- H412Harmful to aquatic life with long-lasting effects
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 31 °C / 87.8 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-20/21/22-34-52/53 |
| Safety statements (S) | 26-36/37/39-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl chlorothiolformate used for?
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Methyl chlorothiolformate is primarily used as a building block and intermediate in organic synthesis for the preparation of various chemical compounds, particularly those containing thioester functionalities or requiring the introduction of the methylthiocarbonyl group.
What is the CAS number and chemical formula for Methyl chlorothiolformate?
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The CAS number is 18369-83-0 and the linear chemical formula is ClCOSCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl chlorothiolformate with an assay of 96%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and technical applications.
How should Methyl chlorothiolformate be handled safely?
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Methyl chlorothiolformate is a Danger classified substance (GHS02, GHS05, GHS06) due to flammability and toxicity. It causes severe skin burns and eye damage, and is harmful if swallowed, in contact with skin, or if inhaled. Handle with extreme care, using appropriate personal protective equipment including gloves, goggles, face shields, and respiratory protection, in a well-ventilated area.
How is Methyl chlorothiolformate packed and shipped?
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Methyl chlorothiolformate is packed and shipped according to UN 2920 specifications for hazardous materials, Class 3 (flammable liquids) with a subsidiary risk of 8 (corrosive), in Packing Group II. We export globally, adhering to all relevant transport regulations.
How can I request a quote or sample of Methyl chlorothiolformate?
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To request a quote or sample, please contact our sales department via the website or direct email, providing your contact details and the quantity required. Our team will respond promptly.
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