R(+)-SKF-81297 hydrobromide
R(+)-SKF-81297 hydrobromide (CAS: 253446-15-0) is a white to off-white solid with a molecular weight of 370.67 g/mol and the empirical formula C16H16ClNO2 · HBr. As a potent dopaminergic agonist, it serves as a valuable research tool in neuroscience and cell biology. Its applications primarily lie in the investigation of dopamine receptor pathways and related cellular signalling mechanisms, contributing to a deeper understanding of neurological processes.
- IUPAC
- R-(+)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
- Synonyms
- R-(+)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
Neuroscience Research
Utilised as a selective dopamine D1 receptor agonist to study dopaminergic neurotransmission and its role in various neurological functions and disorders.
Cell Signalling Studies
Employed to investigate the intracellular signalling cascades activated by D1 receptor stimulation in various cell types.
Pharmacological Tool
Serves as a precise chemical probe for evaluating the efficacy and mechanisms of dopaminergic drugs in preclinical research.
Biochemical Assays
Used in vitro to characterise receptor binding affinities and functional responses of dopamine receptors.
| Molecular weight | 370.67 |
|---|---|
| Empirical formula | C16H16ClNO2 · HBr |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to off-white |
| Solubility | H2O: soluble6 mg/mLDMSO: soluble |
| Optical activity | [α]22/D +15.14°, c = 0.52 in DMF(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccatedprotect from light |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is R(+)-SKF-81297 hydrobromide used for?
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R(+)-SKF-81297 hydrobromide is primarily used as a research tool in neuroscience and cell biology, particularly for studying dopamine D1 receptors and related cellular signalling pathways. It acts as a potent dopaminergic agonist.
What is the CAS number and formula for R(+)-SKF-81297 hydrobromide?
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The CAS number is 253446-15-0 and the empirical formula is C16H16ClNO2 · HBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies R(+)-SKF-81297 hydrobromide with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
How should R(+)-SKF-81297 hydrobromide be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a respirator filter (type N95 or P1). Store desiccated and protected from light.
Is R(+)-SKF-81297 hydrobromide a controlled substance?
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The provided data does not indicate that R(+)-SKF-81297 hydrobromide is a controlled substance. However, researchers should always verify local regulations.
How is R(+)-SKF-81297 hydrobromide packed and shipped?
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R(+)-SKF-81297 hydrobromide is supplied as a white to off-white solid. International shipping and export services are available. Specific packing details can be provided upon request.
How can I request a quote or sample?
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To request a quote or a sample of R(+)-SKF-81297 hydrobromide, please contact the Tech Serve Solutions sales team through our website or by phone.
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