Methyl chloroacetate
Methyl chloroacetate (CAS: 96-34-4), with the linear formula ClCH2COOCH3 and a molecular weight of 108.52 g/mol, is a valuable ester and carbonyl compound. This chemical serves as a key building block in organic synthesis. Its applications include the preparation of specific ammonium chloride esters and the synthesis of complex macrocyclic compounds. Tech Serve Solutions provides this reagent for research and development purposes.
Synthesis of Quaternary Ammonium Compounds
Methyl chloroacetate is employed in the preparation of (carboxymethyl)trimethylammonium chloride esters, acting as a crucial alkylating agent in the formation of these quaternary ammonium salts.
Preparation of Macrocyclic Ethers
This ester can be utilised in the synthesis of complex organic structures, such as the preparation of octakis-(carbethoxymethoxy)calix[8]arene, contributing to the field of supramolecular chemistry.
General Organic Synthesis
As a reactive ester and alkyl halide, methyl chloroacetate is a versatile intermediate for introducing the carboxymethyl group in various chemical transformations and the development of novel compounds.
| Molecular weight | 108.52 |
|---|---|
| Linear formula | ClCH2COOCH3 |
| Assay | 99% |
| Boiling point | 130 °C/740 mmHg(lit.) |
| Density | 1.238 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.422(lit.) |
| Solubility | H2O: insolublealcohol: misciblediethyl ether: miscible |
| Melting point | −33 °C(lit.) |
| Vapour pressure | 10 mmHg (25 °C)5.25 mmHg (20 °C) |
| Vapour density | 3.8 (vs air) |
| Autoignition temp | 869 °F |
| Application | Methyl chloroacetate was used in the preparation of (carboxymethyl) trimethylammonium chloride esters1. It may be used in the synthesis of octakis-(carbethoxymethoxy)calix[8]arene2. |
Hazard statements
- H226Flammable liquid and vapour
- H301Toxic if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H331Toxic if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 47 °C / 116.6 °F |
| Transport (UN / ADR) | UN 2295 3(6.1) / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 10-23/25-37/38-41 |
| Safety statements (S) | 26-37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Expl Lim | 18.5 % |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl chloroacetate used for?
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Methyl chloroacetate is used as a building block in organic synthesis, including the preparation of (carboxymethyl)trimethylammonium chloride esters and octakis-(carbethoxymethoxy)calix[8]arene.
What is the CAS number and chemical formula for Methyl chloroacetate?
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The CAS number is 96-34-4 and the linear formula is ClCH2COOCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl chloroacetate with an assay of 99%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or pharmaceutical grade.
How should Methyl chloroacetate be handled safely?
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Methyl chloroacetate is a hazardous substance. It is flammable and toxic by inhalation and ingestion, causing skin irritation and serious eye damage. Handle with appropriate personal protective equipment including gloves, eye protection, and respiratory protection in a well-ventilated area. Refer to the safety data sheet for detailed handling instructions.
How is Methyl chloroacetate packed and shipped?
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Methyl chloroacetate is packed according to safety regulations for hazardous chemicals and is available for export globally by Tech Serve Solutions.
How can I request a quote or sample for Methyl chloroacetate?
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To request a quote or a sample of Methyl chloroacetate, please contact the Tech Serve Solutions sales team through our website or by phone.
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