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Triisopropylphosphine

CAS 6476-36-4[(CH3)2CH]3PCatalysis & Inorganic

Triisopropylphosphine (CAS: 6476-36-4), with the chemical formula [(CH3)2CH]3P and a molecular weight of 160.24 g/mol, is a basic phosphine ligand. It is a valuable reagent in catalysis and chemical synthesis, particularly in cross-coupling reactions. This compound finds application in various inorganic chemistry processes. Supplied by Tech Serve Solutions, it is typically available in technical grade.

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Triisopropylphosphine ([(CH3)2CH]3P) — chemical structure, CAS 6476-36-4; Chemistry, fine chemical supplied by Tech Serve Solutions
Basic Phosphine LigandsChemical SynthesisCross-CouplingPhosphine CompoundsPhosphine Ligands More...
01 /Applications

Catalysis

Triisopropylphosphine serves as a ligand in homogeneous catalysis. It is employed in transition metal-catalysed reactions, including cross-coupling, where its electronic and steric properties can influence reaction outcomes.

Chemical Synthesis

This phosphine is a building block in organic and organometallic synthesis. Its reactivity makes it useful for introducing phosphine functionalities or as a component in catalyst systems for various transformations.

Inorganic Chemistry

As a Lewis base, Triisopropylphosphine can coordinate to metal centres, forming complexes relevant to inorganic chemistry research and applications. It is used in the preparation of various metal phosphide compounds.

02 /Properties
Molecular weight160.24
Linear formula[(CH3)2CH]3P
Gradetechnical grade
Boiling point81 °C/22 mmHg(lit.)
Density0.839 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.466(lit.)
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H250Catches fire spontaneously if exposed to air
  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P222Do not allow contact with air
  • P231Handle under inert gas
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
  • P422
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point105 °C / 221 °F
Transport (UN / ADR)UN 2845 4.2
Water hazard class (WGK, DE)3
Hazard codes (EU)F,C
Risk statements (R)17-34
Safety statements (S)17-26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
6476-36-4
MDL number
MFCD00015029
PubChem substance
24863218
Beilstein registry
906732
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Triisopropylphosphine used for?

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Triisopropylphosphine is primarily used as a ligand in catalysis, particularly for cross-coupling reactions, and in general chemical synthesis and inorganic chemistry.

What is the CAS number and formula for Triisopropylphosphine?

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The CAS number is 6476-36-4 and the chemical formula is [(CH3)2CH]3P.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Triisopropylphosphine in technical grade. We do not represent this product as USP, BP, or EP grade.

How should Triisopropylphosphine be handled safely?

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Triisopropylphosphine is highly flammable and corrosive. Handle with extreme care, using appropriate personal protective equipment including gloves, goggles, face shield, and respiratory protection. Store under inert atmosphere away from ignition sources.

Is Triisopropylphosphine a controlled substance?

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The provided data does not indicate that Triisopropylphosphine is a controlled substance. However, regulations can vary by region.

How is Triisopropylphosphine packed and shipped?

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Triisopropylphosphine is packed according to safety regulations for hazardous materials. It is exported globally by Tech Serve Solutions, adhering to international shipping standards for dangerous goods.

How can I request a quote or sample of Triisopropylphosphine?

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To request a quote or sample of Triisopropylphosphine, please contact our sales team through the website or by phone, providing your requirements and shipping details.

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