Trichloroacetamide
Trichloroacetamide (CAS 594-65-0) is a chemical compound with the linear formula Cl3CCONH2 and a molecular weight of 162.40 g/mol. It is an amide derived from trichloroacetic acid. This compound serves as a valuable building block in organic synthesis and has been utilised in scientific research, including studies investigating the physiological effects of disinfection byproducts.

Research and Development
Trichloroacetamide is employed in laboratory settings for chemical synthesis and as a reagent in various research applications. Its structure makes it useful for introducing the trichloroacetyl group.
Toxicological Studies
Historically, trichloroacetamide has been used in studies to investigate the health effects of nitrogenous disinfection byproducts. These investigations often utilise techniques such as transcriptomics and metabonomics in animal models.
Organic Synthesis
As an organic building block, trichloroacetamide can be a precursor or intermediate in the synthesis of more complex molecules. It is part of the carbonyl compounds category, valuable for constructing various organic structures.
| Molecular weight | 162.40 |
|---|---|
| Linear formula | Cl3CCONH2 |
| Assay | 99% |
| Boiling point | 238-240 °C(lit.) |
| Application | Trichloroacetamide was used in microarray-based transcriptomics and one-dimensional proton nuclear magnetic resonance based metabonomics to investigate the health effects of nitrogenous disinfection byproducts of trichloroacetamide in mice1. |
| Melting point | 139-141 °C(lit.) |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trichloroacetamide used for?
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Trichloroacetamide is used in chemical synthesis as an organic building block. It has also been utilised in research studies, for instance, to investigate the health effects of nitrogenous disinfection byproducts in animal models.
What are the CAS number and formula for Trichloroacetamide?
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The CAS number for Trichloroacetamide is 594-65-0, and its linear formula is Cl3CCONH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Trichloroacetamide with a minimum purity of 99%. This product is suitable for research and general laboratory use. TSS does not represent this product as USP, BP, or EP grade.
How should Trichloroacetamide be handled safely?
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Trichloroacetamide is classified as a Warning substance (GHS07) and causes serious eye irritation (H319). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 US recommended). Ensure good ventilation and follow precautionary statements P305 + P351 + P338.
Is Trichloroacetamide a controlled substance?
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The provided data does not indicate that Trichloroacetamide is a controlled substance.
How is Trichloroacetamide packed and shipped?
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Trichloroacetamide is carefully packed to ensure integrity during transit. As a global supplier and exporter, TSS adheres to all relevant regulations for shipping chemical compounds.
How can I request a sample or quote for Trichloroacetamide?
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To request a sample or a quotation for Trichloroacetamide, please contact our sales team via the website or email, providing your specific requirements and shipping details.
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