Retrorsine

CAS 480-54-6C18H25NO6Cell Biology

Retrorsine (CAS: 480-54-6) is a pyrrolizidine alkaloid with the molecular formula C18H25NO6 and a molecular weight of 351.39 g/mol. It is primarily recognised for its role in biological research, particularly in studies concerning apoptosis and cell cycle regulation. This compound serves as a valuable tool for scientists investigating cellular mechanisms within cell biology and neuroscience, contributing to a deeper understanding of cell signaling pathways.

IUPAC: β-Longilobine,12,18-Dihydroxysenecionan-11,16-dione

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Retrorsine (C18H25NO6) — chemical structure, CAS 480-54-6; Life Science, fine chemical supplied by Tech Serve Solutions

Apoptosis and Cell CycleCell BiologyCell Cycle ProteinsAntibodies and ReagentsCell Cycle Regulators

01 /Applications

Apoptosis and Cell Cycle Research

Retrorsine is utilised as a research chemical to investigate the mechanisms of programmed cell death (apoptosis) and the regulation of the cell cycle. Its effects on cellular processes make it a useful compound for studying these fundamental biological pathways.

Cell Biology Studies

As a compound studied within cell biology, Retrorsine aids researchers in understanding cellular functions and responses. It can be employed in experiments designed to probe cellular health, stress responses, and regulatory mechanisms.

Cell Signaling Investigations

This chemical is relevant in the study of cell signaling pathways, which are crucial for intercellular communication and cellular responses. Researchers may use Retrorsine to explore how signaling cascades are affected by specific molecular interactions.

Neuroscience Research Tool

Within neuroscience, Retrorsine can be applied to investigate cellular processes relevant to the nervous system. Its use assists in elucidating complex biological pathways and the biochemical interactions occurring in neuronal cells.

02 /Properties

Molecular weight	351.39
Empirical formula	C18H25NO6
Assay	≥90% (HPLC)
Melting point	208-211 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash thoroughly after handling
P301IF SWALLOWED

Protective equipment	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 1544 6.1/PG 2
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	25
Safety statements (S)	22-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

480-54-6

PubChem substance

24899338

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Retrorsine used for?

Retrorsine is used in scientific research, particularly in studies concerning apoptosis, cell cycle regulation, cell biology, cell signaling, and neuroscience.

What are the CAS number and chemical formula for Retrorsine?

The CAS number for Retrorsine is 480-54-6, and its chemical formula is C18H25NO6.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Retrorsine with a minimum purity of 90% as determined by HPLC. TSS does not represent this product as USP, BP, or EP grade.

How should Retrorsine be handled?

Retrorsine is classified as acutely toxic (Danger, H300). Handling requires appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 (EN 143) respirator cartridges. Avoid ingestion and ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive handling information.

Is Retrorsine a controlled substance?

The provided data does not indicate that Retrorsine is a scheduled or controlled substance.

How is Retrorsine packed, shipped, and exported?

Retrorsine is packed according to safety regulations for hazardous materials (UN 1544, 6.1/PG 2). As a global supplier, Tech Serve Solutions is experienced in exporting chemicals worldwide, adhering to all relevant international shipping and customs regulations.