Reversine
Reversine (CAS: 656820-32-5), with the molecular formula C21H27N7O and a molecular weight of 393.49 g/mol, is a potent and selective antagonist of adenosine receptors. It is widely utilised in biochemical research for its ability to modulate purinergic signalling pathways. This compound serves as a valuable tool in studies concerning cell biology, cell signalling, neuroscience, and neurotransmission, aiding in the investigation of complex biological processes.
- IUPAC
- 2-(4-Morpholinoanilino)-6-cyclohexylaminopurine

Adenosine Receptor Antagonism
Reversine acts as a selective antagonist for adenosine receptors, making it an invaluable tool for researchers investigating purinergic signalling. It allows for the precise study of the roles of these receptors in various physiological and pathological processes.
Neuroscience Research
This compound is employed in neuroscience to explore the intricate mechanisms of neurotransmission and neuromodulation. Its activity on adenosine receptors can shed light on neuronal function and potential therapeutic targets within the central nervous system.
Cellular Signaling Studies
As a bioactive small molecule, Reversine is instrumental in dissecting complex cellular signalling cascades. Its application helps researchers understand how extracellular signals are transduced and influence cellular behaviour and responses.
Stem Cell Biology
Reversine finds application in stem cell biology, where it can influence cell fate and differentiation processes. Its role in modulating adenosine receptor activity contributes to understanding the microenvironment of stem cells.
| Molecular weight | 393.49 |
|---|---|
| Empirical formula | C21H27N7O |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Solubility | DMSO: soluble7 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)rat ... Adora3(25370) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Reversine used for?
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Reversine is used in biochemical research as a potent and selective antagonist of adenosine receptors, facilitating studies in cell biology, cell signalling, neuroscience, and neurotransmission.
What are the CAS number and formula for Reversine?
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The CAS number for Reversine is 656820-32-5, and its molecular formula is C21H27N7O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Reversine with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Reversine be handled safely?
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Reversine is classified as a Warning substance and is harmful if swallowed (H302). When handling, wear a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation.
How is Reversine shipped and exported?
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Reversine is typically stored at 2-8°C. Tech Serve Solutions expertly handles the packing, shipping, and exporting of chemicals globally, adhering to all relevant regulations.
How can I request a quote or sample for Reversine?
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To request a quote or a sample of Reversine, please visit our website or contact our sales department directly.
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