Trichloro(3-cyanopropyl)silane
Trichloro(3-cyanopropyl)silane (CAS: 1071-27-8, C4H6Cl3NSi) is a silicon-based compound with a molecular weight of 202.54 g/mol. This versatile reagent is primarily used in chemical synthesis, particularly for the introduction of the 3-cyanopropylsilyl group. Its reactivity makes it a valuable component in the development of novel materials and organic transformations, serving as a key intermediate in various research and industrial applications.
- IUPAC
- 3-Cyanopropyltrichlorosilane,4-Trichlorosilylbutyronitrile
- Synonyms
- 3-Cyanopropyltrichlorosilane4-Trichlorosilylbutyronitrile

Chemical Synthesis Intermediate
Trichloro(3-cyanopropyl)silane serves as a crucial intermediate in organic synthesis. It is employed to introduce the 3-cyanopropylsilyl moiety onto various substrates, enabling further functionalization or modification.
Protecting and Derivatizing Reagent
In analytical chemistry and organic synthesis, this compound can function as a derivatizing agent. It reacts with functional groups to form derivatives that may have improved chromatographic or spectroscopic properties.
Surface Modification
Organosilanes like Trichloro(3-cyanopropyl)silane are often used to modify the surfaces of materials, such as silica or glass. This can alter surface properties like hydrophobicity or reactivity for specific applications.
| Molecular weight | 202.54 |
|---|---|
| Empirical formula | C4H6Cl3NSi |
| Assay | ≥98.0% (GC) |
| Boiling point | 237-238 °C(lit.) |
| Density | 1.302 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.464 |


Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 92 °C / 197.6 °F |
| Transport (UN / ADR) | UN 2987 8 / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34-37 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trichloro(3-cyanopropyl)silane used for?
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Trichloro(3-cyanopropyl)silane is primarily used in chemical synthesis as an intermediate and as a protecting or derivatizing reagent, including for surface modification applications.
What are the CAS number and formula for Trichloro(3-cyanopropyl)silane?
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The CAS number for Trichloro(3-cyanopropyl)silane is 1071-27-8, and its empirical formula is C4H6Cl3NSi.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Trichloro(3-cyanopropyl)silane with an assay of ≥98.0% (GC). We do not represent this product as meeting USP, BP, EP, or any other pharmacopoeia standards.
How should Trichloro(3-cyanopropyl)silane be handled safely?
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Trichloro(3-cyanopropyl)silane is a corrosive substance that reacts violently with water. Handle with extreme care in a well-ventilated area, wearing appropriate personal protective equipment including gloves, goggles, a face shield, and a suitable respirator. Avoid contact with skin, eyes, and clothing. Refer to the Safety Data Sheet for detailed handling instructions.
How is Trichloro(3-cyanopropyl)silane packed and shipped?
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Trichloro(3-cyanopropyl)silane is packed and shipped according to relevant dangerous goods regulations (UN 2987, Class 8, PG II). Contact TSS for specific packaging and export details.
How can I request a sample or quote for Trichloro(3-cyanopropyl)silane?
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To request a sample or a quote for Trichloro(3-cyanopropyl)silane, please contact our sales team via the website or listed contact information.
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