Ethyl 2-nitropropionate
Ethyl 2-nitropropionate (CAS: 2531-80-8), with the chemical formula CH3CH(NO2)CO2C2H5 and a molecular weight of 147.13 g/mol, is a valuable organic building block. This nitroester serves as a versatile intermediate in chemical synthesis, particularly within the realms of organic chemistry and the preparation of more complex molecules. Its reactive functional groups make it a useful reagent in various synthetic pathways.

Organic Synthesis Intermediate
Ethyl 2-nitropropionate acts as a key building block in the synthesis of various organic compounds. Its nitro and ester functionalities allow for diverse chemical transformations.
Pharmaceutical Precursor
It can be utilised in the multi-step synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs). The molecule's structure lends itself to incorporation into complex drug molecules.
Specialty Chemical Production
This compound finds application in the production of specialty chemicals where specific nitroalkane or ester derivatives are required. Its properties are leveraged in fine chemical manufacturing.
| Molecular weight | 147.13 |
|---|---|
| Linear formula | CH3CH(NO2)CO2C2H5 |
| Assay | 96% |
| Boiling point | 75-76 °C/9 mmHg(lit.) |
| Density | 1.13 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.421(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 89 °C / 192.2 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 2-nitropropionate used for?
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Ethyl 2-nitropropionate (CAS: 2531-80-8) is primarily used as a versatile intermediate in organic synthesis, including the preparation of pharmaceutical intermediates and specialty chemicals.
What are the CAS number and chemical formula for Ethyl 2-nitropropionate?
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The CAS number is 2531-80-8 and the chemical formula is CH3CH(NO2)CO2C2H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl 2-nitropropionate with an assay of 96%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should Ethyl 2-nitropropionate be handled safely?
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Ethyl 2-nitropropionate is a Warning substance (GHS07) with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Handle with appropriate personal protective equipment including eyeshields, gloves, and suitable respiratory protection, in a well-ventilated area.
Is Ethyl 2-nitropropionate a controlled substance?
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The provided data does not indicate that Ethyl 2-nitropropionate is a controlled substance.
How is Ethyl 2-nitropropionate packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific packaging and shipping details are available upon request, adhering to international transport regulations.
How can I request a quote or sample for Ethyl 2-nitropropionate?
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To request a quote or sample, please contact our sales team through the website or by phone. Provide the product name and CAS number (2531-80-8) for prompt service.
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