8-(Di-tert-butylphosphinooxy)quinoline
8-(Di-tert-butylphosphinooxy)quinoline (CAS: 1100332-44-2) is an organophosphorus compound with the molecular formula C17H24NOP and a molecular weight of 289.35 g/mol. This chemical is primarily utilised in catalysis, particularly within homogeneous palladium-catalysed reactions. Its structure lends itself to applications in chemical synthesis, serving as a valuable reagent for organic chemists seeking to develop novel synthetic pathways and improve existing methodologies.

Homogeneous Palladium Catalysis
This compound functions as a ligand in homogeneous palladium catalysis. It is employed in various cross-coupling reactions, facilitating the formation of carbon-carbon and carbon-heteroatom bonds.
Chemical Synthesis Reagent
As a versatile reagent, 8-(Di-tert-butylphosphinooxy)quinoline is used in the synthesis of complex organic molecules. Its properties are beneficial for advancing research in synthetic organic chemistry and drug discovery.
Ligand Development
The unique phosphinooxyquinoline structure makes it an interesting candidate for the development of novel catalytic systems. Research may explore its efficacy in a broader range of catalytic transformations.
| Molecular weight | 289.35 |
|---|---|
| Empirical formula | C17H24NOP |
| Melting point | 55-62 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 8-(Di-tert-butylphosphinooxy)quinoline primarily used for?
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This compound is primarily used as a ligand in homogeneous palladium catalysis and as a reagent in chemical synthesis.
What is the CAS number and chemical formula for 8-(Di-tert-butylphosphinooxy)quinoline?
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The CAS number is 1100332-44-2 and the empirical formula is C17H24NOP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. Specific purity and assay details are available on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should 8-(Di-tert-butylphosphinooxy)quinoline be handled?
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Caution is advised when handling this chemical. It is classified as causing skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including gloves, eye protection, and respiratory protection if needed, should be used in a well-ventilated area.
How is this chemical packed and shipped?
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Tech Serve Solutions exports chemicals globally, ensuring appropriate packaging for safe transit and compliance with international shipping regulations.
How can I request a sample or quote?
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To request a sample or obtain a quotation, please contact our sales team through the website or by phone, providing the product name and CAS number.
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