6,6′-Bis(4-(S)-isopropyl-2-oxazolinyl)-2,2′-bipyridine
6,6′-Bis(4-(S)-isopropyl-2-oxazolinyl)-2,2′-bipyridine (CAS: 147409-41-4) is a chiral bipyridine-derived ligand with the molecular formula C22H26N4O2 and a molecular weight of 378.47 g/mol. It is recognised for its utility in asymmetric synthesis, particularly as a ligand in catalytic processes. With an assay of 96%, this compound is supplied by Tech Serve Solutions for research and development purposes.
- IUPAC
- Bipymox
- Synonyms
- 147409-41-4C22H26N4O2Bipymox

Asymmetric Hydrosilation of Ketones
This compound serves as a chiral ligand in the asymmetric hydrosilation of ketones. This catalytic process enables the stereoselective reduction of ketone functionalities, leading to the formation of chiral alcohols.
Catalysis in Chemical Synthesis
As a bipyridine-type ligand, it is employed in various catalytic systems within organic synthesis. Its structure allows for coordination with metal centres, influencing the reactivity and selectivity of catalytic transformations.
Chiral Ligand for Metal Complexes
The compound's chiral oxazoline moieties make it suitable for forming chiral metal complexes. These complexes can be investigated for their catalytic activity in stereoselective reactions.
| Molecular weight | 378.47 |
|---|---|
| Empirical formula | C22H26N4O2 |
| Assay | 96% |
| Optical activity | [α]/D -97.0°, c = 0.5% in dichloromethane |
| Application | Ligand used in the asymmetric hydrosilation of ketones1. |
| Melting point | 185-190 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6,6′-Bis(4-(S)-isopropyl-2-oxazolinyl)-2,2′-bipyridine used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis, notably in the hydrosilation of ketones.
What is the CAS number and molecular formula?
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The CAS number is 147409-41-4, and the empirical formula (Hill notation) is C22H26N4O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 96%. It is provided for research and development; we do not represent it as USP, BP, EP, or pharmacopoeia grade.
How should 6,6′-Bis(4-(S)-isopropyl-2-oxazolinyl)-2,2′-bipyridine be handled?
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This compound is classified as a Warning. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid breathing dust/fume/gas/mist/vapours/spray.
Is this chemical available for export and how is it shipped?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific shipping and export details can be provided upon request.
How can I request a sample or quote?
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Please contact our sales team directly through the website or by phone to request a sample or a quotation for this product.
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