Trichloroacetyl chloride
Trichloroacetyl chloride (CAS 76-02-8), with the linear formula Cl 3 CCOCl and a molecular weight of 181.83 g/mol, is a reactive acid halide. It serves as a valuable intermediate in organic synthesis, particularly in the preparation of heterocyclic compounds and functionalized molecules. Its chemical reactivity makes it a useful building block for various chemical transformations. Tech Serve Solutions supplies this compound for research and industrial applications.
Synthesis of Heterocyclic Compounds
Trichloroacetyl chloride has been employed in the preparation of dihydro-1H-benzindoles, demonstrating its utility in constructing complex ring systems.
Preparation of Benzoxazolones
This reagent is used in the synthesis of 3-alkylbenzoxazolones, showcasing its role in the formation of pharmacologically relevant scaffolds.
Organic Synthesis Intermediate
As a reactive acylating agent, trichloroacetyl chloride functions as a key building block in various organic transformations and functional group introductions.
| Molecular weight | 181.83 |
|---|---|
| Linear formula | Cl3CCOCl |
| Assay | 99% |
| Boiling point | 114-116 °C(lit.) |
| Density | 1.629 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.470(lit.) |
| Vapour pressure | 16 mmHg (20 °C) |
| Melting point | −57 °C(lit.) |
| Application | Trichloroacetyl chloride was used in the preparation of dihydro-1H-benzindoles1. It was also used in the synthesis of 3-alkylbenzoxazolones2. |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H330Fatal if inhaled
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 100 °C / 212 °F |
| Transport (UN / ADR) | UN 2442 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 14-22-26-34 |
| Safety statements (S) | 26-28-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trichloroacetyl chloride used for?
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Trichloroacetyl chloride is used in organic synthesis, including the preparation of dihydro-1H-benzindoles and 3-alkylbenzoxazolones, and as a general building block for chemical synthesis.
What is the CAS number and formula for Trichloroacetyl chloride?
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The CAS number for Trichloroacetyl chloride is 76-02-8, and its linear formula is Cl 3 CCOCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions typically supplies Trichloroacetyl chloride with an assay of 99%. This product is not represented as USP, BP, or EP grade. For specific purity requirements, please contact us.
How should Trichloroacetyl chloride be handled safely?
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Trichloroacetyl chloride is a Danger hazard that reacts violently with water. It is corrosive and toxic by inhalation. Always handle with extreme care, using appropriate personal protective equipment such as a full-face respirator, gloves, and goggles in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling instructions.
Is Trichloroacetyl chloride shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Trichloroacetyl chloride, and can arrange for international shipments.
How can I request a sample or quote for Trichloroacetyl chloride?
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To request a sample or a quote for Trichloroacetyl chloride, please visit the Tech Serve Solutions website or contact our sales team directly.
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