1-Ethynyl-2,4-difluorobenzene
1-Ethynyl-2,4-difluorobenzene (CAS: 302912-34-1) is a fluorinated alkynyl building block with the molecular formula HC≡CC₆H₃F₂ and a molecular weight of 138.11 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals. Its unique structure, featuring both an ethynyl group and two fluorine atoms on the benzene ring, allows for diverse chemical transformations.
- Synonyms
- HC≡CC6H3F2
Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs) where fluorinated aromatic moieties are required for modulating drug properties such as metabolic stability and binding affinity.
Agrochemical Development
Serves as a key building block for novel pesticides, herbicides, and fungicides, leveraging the effects of fluorine substitution on biological activity and environmental persistence.
Materials Science Research
Incorporated into advanced materials, such as polymers or organic electronic components, to impart specific thermal, electronic, or optical properties due to its fluorinated aromatic structure.
Organic Synthesis Reagent
A versatile reagent for introducing the 2,4-difluorophenylacetylene fragment into complex organic molecules via cross-coupling reactions or other synthetic methodologies.
| Molecular weight | 138.11 |
|---|---|
| Linear formula | HC≡CC6H3F2 |
| Assay | 97% |
| Melting point | 29-32 °C(lit.) |
Hazard statements
- H228Flammable solid
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 33 °C / 91.4 °F |
| Transport (UN / ADR) | UN 1325 4.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Ethynyl-2,4-difluorobenzene used for?
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1-Ethynyl-2,4-difluorobenzene is primarily used as a building block in organic synthesis, particularly for developing pharmaceuticals, agrochemicals, and advanced materials. Its structure allows for the introduction of fluorinated aromatic units into larger molecules.
What is the CAS number and formula for 1-Ethynyl-2,4-difluorobenzene?
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The CAS number is 302912-34-1, and the linear formula is HC≡CC₆H₃F₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Ethynyl-2,4-difluorobenzene with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 1-Ethynyl-2,4-difluorobenzene be handled safely?
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1-Ethynyl-2,4-difluorobenzene is a flammable solid (H228) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment including eyeshields, gloves, and respiratory protection in a well-ventilated area. Keep away from heat, sparks, and open flames (P210).
How is 1-Ethynyl-2,4-difluorobenzene packed, shipped, and exported?
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1-Ethynyl-2,4-difluorobenzene is packed according to safety regulations for flammable solids and chemical reagents. We are experienced in exporting fine chemicals globally, adhering to all international shipping and customs requirements.
How can I request a sample or quote for 1-Ethynyl-2,4-difluorobenzene?
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To request a sample or a quote, please contact our sales team through the website or by phone. Please provide your contact details and the quantity required.
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