1-Ethynyl-3,5-difluorobenzene
1-Ethynyl-3,5-difluorobenzene (CAS: 151361-87-4) is a fluorinated aromatic compound with the molecular formula C8H4F2 and a molecular weight of 138.11 g/mol. This liquid chemical serves as a valuable building block in organic synthesis. Its difluorinated phenyl ring and terminal alkyne functionality make it suitable for various chemical reactions, particularly in the development of novel materials and pharmaceutical intermediates.
- Synonyms
- F2C6H3C≡CH
Organic Synthesis Building Block
Utilised as a key intermediate in the construction of complex organic molecules. The presence of both fluorine atoms and an ethynyl group offers unique reactivity for further functionalization.
Pharmaceutical Intermediate
Serves as a precursor in the synthesis of active pharmaceutical ingredients (APIs) where fluorinated aromatic moieties are desired for modifying pharmacokinetic properties.
Materials Science Research
Applicable in the development of novel polymers and advanced materials, leveraging the electronic properties imparted by the difluorobenzene structure.
| Molecular weight | 138.11 |
|---|---|
| Linear formula | F2C6H3C≡CH |
| Assay | 97% |
| Form | liquid |
| Boiling point | 123-124 °C(lit.) |
| Density | 1.163 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4910(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 33 °C / 91.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Ethynyl-3,5-difluorobenzene used for?
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1-Ethynyl-3,5-difluorobenzene is primarily used as a building block in organic synthesis, including the development of pharmaceutical intermediates and novel materials.
What is the CAS number and formula for 1-Ethynyl-3,5-difluorobenzene?
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The CAS number is 151361-87-4, and its linear formula is F2C6H3C≡CH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Ethynyl-3,5-difluorobenzene with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 1-Ethynyl-3,5-difluorobenzene be handled?
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This compound is a flammable liquid and vapour (H226), and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and use in a well-ventilated area. Ensure ignition sources are kept away.
How is 1-Ethynyl-3,5-difluorobenzene packed and shipped?
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1-Ethynyl-3,5-difluorobenzene is packed and shipped in compliance with relevant regulations for hazardous materials. As a global supplier and exporter, TSS ensures appropriate packaging for international transport.
How can I request a quote or sample for 1-Ethynyl-3,5-difluorobenzene?
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To request a quote or sample, please contact our sales team through the website or by phone, providing your requirements and shipping details.
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