TBB

CAS 17374-26-4C6HN3Br4Cell Biology

4,5,6,7-Tetrabromobenzimidazole (CAS: 17374-26-4), with the empirical formula C6HN3Br4 and a molecular weight of 434.71 g/mol, is a white solid chemical compound. It is primarily utilised as a research chemical in biochemical and cell biology studies. Its notable application includes investigating casein kinase 2-dependent phosphorylation, contributing to a deeper understanding of cellular signaling pathways and DNA damage response mechanisms.

IUPAC: 4,5,6,7-Tetrabromo-2-azabenzimidazole,4,5,6,7-Tetrabromobenzotriazole,NSC 231634,TBBt
Synonyms: 4,5,6,7-Tetrabromobenzimidazole4,5,6,7-TetrabromobenzotriazoleNSC 231634TBBt

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TBB (C6HN3Br4) — chemical structure, CAS 17374-26-4; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCasein Kinase (CK)Cell BiologyKinase/Phosphatase BiologyT More...

01 /Applications

Investigating Kinase Activity

TBB serves as a valuable tool in research settings to explore the function of casein kinase 2 (CK2). It has been employed in studies to understand CK2-dependent phosphorylation of key proteins involved in cellular processes.

Cellular Signaling Research

This compound aids in dissecting cellular signaling pathways, particularly those involving serine/threonine kinases. Understanding these pathways is crucial for comprehending cell growth, differentiation, and disease progression.

DNA Damage Response Studies

TBB has been used in research to study the phosphorylation of DNA damage mediator proteins, such as MDC1. This contributes to the broader understanding of how cells respond to and repair DNA damage.

02 /Properties

Molecular weight	434.71
Empirical formula	C6HN3Br4
Assay	≥98% (HPLC)
Form	solid
Colour	white
Solubility	DMSO: soluble28 mg/mL
Storage temperature	2-8°C
Application	TBB was used to study casein kinase 2-dependent phosphorylation of DNA damage mediator protein MDC1.1

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

17374-26-4

MDL number

MFCD06411399

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is TBB primarily used for?

TBB is primarily used in research for studying casein kinase 2-dependent phosphorylation and investigating cellular signaling pathways, particularly in the context of DNA damage response.

What are the CAS number and formula for TBB?

The CAS number for TBB is 17374-26-4, and its empirical formula is C6HN3Br4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies TBB with a purity of ≥98% (HPLC). It is supplied as a research-grade chemical and is not intended for pharmaceutical, food, or any other use requiring pharmacopoeia compliance.

What are the safety and handling precautions for TBB?

When handling TBB, it is essential to use personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound is classified with WGK Germany 3, indicating a high hazard level.

How is TBB stored and shipped?

TBB should be stored at 2-8°C. Tech Serve Solutions ensures that all chemicals are packed and exported in compliance with international shipping regulations for hazardous materials.