Necrostatin-7

CAS 351062-08-3C16H10FN5OS2Cell Biology

Necrostatin-7 (CAS 351062-08-3), with the empirical formula C16H10FN5OS2 and molecular weight 371.41 g/mol, is a chemical compound relevant to apoptosis and cell cycle research. It is primarily utilised as a research tool in cell biology, particularly for investigating programmed cell death mechanisms and cell cycle regulation. Its specific inhibitory properties make it valuable in experimental settings.

IUPAC: 5-[[3-(4-Fluorophenyl)-1H-pyrazol-4-yl]methylene]-2-imino-3-(2-thiazolyl)-4-thiazolidinone,Nec-7
Synonyms: Nec-7

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Necrostatin-7 (C16H10FN5OS2) — chemical structure, CAS 351062-08-3; Life Science, fine chemical supplied by Tech Serve Solutions

Apoptosis and Cell CycleCell BiologyCell Cycle ProteinsAntibodies and ReagentsCell Cycle Regulators

01 /Applications

Apoptosis Research

Necrostatin-7 serves as a key reagent in studying the intricate pathways of programmed cell death (apoptosis). Its ability to modulate these processes aids researchers in understanding cellular fate decisions.

Cell Cycle Regulation Studies

This compound is employed to investigate the control mechanisms governing the cell cycle. Researchers use Necrostatin-7 to explore how cellular progression through different phases is regulated and how this can be experimentally influenced.

Cell Signaling Investigations

Necrostatin-7 is utilized in research focused on cellular communication pathways, particularly those implicated in cell death and survival signaling cascades within biological systems.

02 /Properties

Molecular weight	371.41
Empirical formula	C16H10FN5OS2
Assay	≥98% (HPLC)
Solubility	DMSO: >10 mg/mL (with warming)
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

351062-08-3

05 /Additional specifications

Storage Condition	desiccated

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Necrostatin-7 used for?

Necrostatin-7 is used in research for studying apoptosis, cell cycle regulation, and cell signaling pathways.

What are the CAS number and molecular formula for Necrostatin-7?

The CAS number for Necrostatin-7 is 351062-08-3, and its molecular formula is C16H10FN5OS2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Necrostatin-7 with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Necrostatin-7 be handled safely?

Necrostatin-7 is classified with GHS07 symbol and a Warning signal word, indicating it is harmful if swallowed (H302). Handle with appropriate personal protective equipment in a well-ventilated area. Consult the Safety Data Sheet for comprehensive handling information.

How is Necrostatin-7 shipped and exported?

Necrostatin-7 is shipped and exported under controlled conditions appropriate for research chemicals, adhering to all relevant international regulations for hazardous materials.

How can I request a sample or quote for Necrostatin-7?

To request a sample or quote for Necrostatin-7, please contact our sales department via the website or by phone, providing your specific requirements and shipping details.