TBBz

CAS 577779-57-8C7H2N2Br4Cell Biology

Tech Serve Solutions supplies 4,5,6,7-Tetrabromobenzimidazole (CAS: 577779-57-8; C7H2N2Br4), a potent CK2 inhibitor. With a molecular weight of 433.72, this research-grade compound is presented as a powder. TBBz has been utilized in scientific investigations involving cell biology, kinase/phosphatase research, and neuroscience, specifically as an inhibitor of Casein Kinase 2 (CK2) in experimental models such as HeLa cells and rat septal neurons.

IUPAC: 4,5,6,7-Tetrabromobenzimidazole
Synonyms: 4,5,6,7-Tetrabromobenzimidazole

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TBBz (C7H2N2Br4) — chemical structure, CAS 577779-57-8; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCell BiologyKinase/Phosphatase BiologyProtein Kinase InhibitorsT More...

01 /Applications

CK2 Inhibition in Cellular Studies

TBBz has been employed as a selective inhibitor of Casein Kinase 2 (CK2). Its application in experimental settings allows researchers to investigate the role of CK2 in various cellular processes and signaling pathways.

Neuroscience Research Tool

This compound has been used in studies involving rat septal neurons to explore the effects of CK2 inhibition on neuronal function and signaling within the central nervous system.

Cell Biology Investigations

As a bioactive small molecule, TBBz serves as a valuable tool in cell biology research, enabling the examination of CK2's involvement in cellular mechanisms and potential therapeutic targets.

02 /Properties

Molecular weight	433.72
Empirical formula	C7H2N2Br4
Assay	≥98% (HPLC)
Form	powder
Solubility	DMSO: >10 mg/mL at 60 °C, clear
Storage temperature	2-8°C
Application	TBBz has been used as a CK2 inhibitor in HeLa cells1 and rat septal neurons2.

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed
H319Causes serious eye irritation

Precautionary statements

P301IF SWALLOWED
P305IF IN EYES

Protective equipment	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	25-36
Safety statements (S)	26-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

577779-57-8

05 /Additional specifications

Storage Condition	under inert gas

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is TBBz used for?

TBBz is used as a CK2 inhibitor in research settings, with documented applications in cell biology studies using HeLa cells and in neuroscience research involving rat septal neurons.

What is the CAS number and formula for TBBz?

The CAS number for TBBz is 577779-57-8, and its empirical formula is C7H2N2Br4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies TBBz with an assay of ≥98% (HPLC). This is a research-grade chemical and is not represented as USP, BP, or EP.

How should TBBz be handled and stored?

TBBz is classified as a Danger signal word compound with H301 (Toxic if swallowed) and H319 (Causes serious eye irritation) hazards. It should be handled with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges. Store under inert gas at 2-8°C.