Spermine dihydrate
Spermine dihydrate (CAS: 403982-64-9) is a polyamine with the chemical formula NH2(CH2)3NH(CH2)4NH(CH2)3NH2 · 2H2O. This compound, with a molecular weight of 238.37 g/mol, is a significant biological molecule involved in cell growth and division. It is commonly employed in biochemical research, particularly within cell biology studies concerning cellular processes and function.
- IUPAC
- Gerontine,Musculamine,N,N′-Bis(3-aminopropyl)-1,4-diaminobutane,Neuridine
- Synonyms
- GerontineMusculamineN,N′-Bis(3-aminopropyl)-1,4-diaminobutaneNeuridine

Cell Biology Research
Spermine dihydrate is widely used as a tool in cell biology to investigate the roles of polyamines in cellular processes such as DNA replication, transcription, and cell proliferation. Its ability to interact with nucleic acids makes it valuable for studying chromatin structure and gene expression.
Biochemical Assays
This compound serves as a reagent in various biochemical assays and experiments. It can be used to stabilise nucleic acids or to study protein-nucleic acid interactions in vitro.
Investigating Cellular Growth
Due to its involvement in natural cell growth mechanisms, spermine dihydrate is utilised in research aiming to understand and potentially modulate cell cycle progression and differentiation.
| Molecular weight | 238.37 |
|---|---|
| Linear formula | NH2(CH2)3NH(CH2)4NH(CH2)3NH2 · 2H2O |
| Assay | ≥99.5% (GC) |
| Solubility | H2O: soluble1 M at 20 °C, clear, colorless |
| pH | 12.0-13.5 (25 °C, 1 M in H2O) |
| Storage temperature | 2-8°C |
| Impurities tested | insoluble matter, passes filter test |
| Melting point | 63-64 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3259PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
| Anion traces | chloride (Cl-): ≤50 mg/kgsulfate (SO42-): ≤50 mg/kg |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Uv Absorption | λ: 260 nm Amax: 0.20λ: 280 nm Amax: 0.20 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Spermine dihydrate used for?
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Spermine dihydrate is primarily used in cell biology research to investigate the roles of polyamines in cellular processes like DNA replication, transcription, and cell proliferation, as well as for biochemical assays and studying cellular growth mechanisms.
What is the CAS number and chemical formula for Spermine dihydrate?
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The CAS number for Spermine dihydrate is 403982-64-9, and its chemical formula is NH2(CH2)3NH(CH2)4NH(CH2)3NH2 · 2H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Spermine dihydrate with a minimum purity of ≥99.5% (GC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Spermine dihydrate be handled?
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Spermine dihydrate is classified as Danger with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, is essential. Handle in a well-ventilated area and avoid contact with skin, eyes, and clothing.
Is Spermine dihydrate available for international export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Spermine dihydrate, fulfilling orders worldwide.
How can I request a quote or sample for Spermine dihydrate?
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To request a quote or a sample of Spermine dihydrate, please contact the Tech Serve Solutions sales team via our website or designated contact channels.
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