3-(Trifluoromethoxy)benzenesulfonyl chloride
3-(Trifluoromethoxy)benzenesulfonyl chloride (CAS 220227-84-9; CF3OC6H4SO2Cl) is a key organic building block for chemical synthesis. This sulfonyl halide compound, with a molecular weight of 260.62 g/mol, is primarily utilised as an intermediate in the preparation of more complex organic molecules. Its reactivity makes it valuable in research and development settings for constructing specialised chemical structures.
Organic Synthesis Intermediate
Serves as a versatile building block in the synthesis of diverse organic compounds. Its sulfonyl chloride functionality readily participates in reactions like sulfonylation, enabling the introduction of the 3-(trifluoromethoxy)benzenesulfonyl group into target molecules.
Pharmaceutical Research
Utilised in medicinal chemistry for the development of novel pharmaceutical agents. The trifluoromethoxy group can impart desirable pharmacokinetic properties, making this compound a valuable precursor in drug discovery programmes.
Agrochemical Development
Employed in the synthesis of new agrochemicals, such as pesticides and herbicides. The unique electronic and lipophilic properties conferred by the trifluoromethoxy moiety can contribute to enhanced efficacy and targeted activity.
| Molecular weight | 260.62 |
|---|---|
| Linear formula | CF3OC6H4SO2Cl |
| Assay | 97% |
| Boiling point | 229-230 °C(lit.) |
| Density | 1.530 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4760(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Trifluoromethoxy)benzenesulfonyl chloride used for?
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3-(Trifluoromethoxy)benzenesulfonyl chloride (CAS 220227-84-9) is primarily used as an intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals.
What are the CAS number and formula for 3-(Trifluoromethoxy)benzenesulfonyl chloride?
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The CAS number is 220227-84-9 and the molecular formula is CF3OC6H4SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(Trifluoromethoxy)benzenesulfonyl chloride with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the main hazards associated with this chemical?
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This compound is classified as Danger, indicated by GHS05 symbol. It causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including face shields, gloves, and respiratory protection, is mandatory.
How is 3-(Trifluoromethoxy)benzenesulfonyl chloride shipped?
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This chemical is shipped as UN 3265, Class 8, Packing Group II, adhering to stringent international regulations for hazardous materials transport.
How can I request a quote or sample?
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To request a quote or sample of 3-(Trifluoromethoxy)benzenesulfonyl chloride, please contact our sales department through the website or by phone.
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