3-(Trifluoromethoxy)aniline
3-(Trifluoromethoxy)aniline (CAS: 1535-73-5), with the molecular formula CF3OC6H4NH2 and a molar mass of 177.12 g/mol, is a valuable aromatic amine. This organic compound serves as a crucial building block in chemical synthesis, particularly for pharmaceuticals and agrochemicals. Its trifluoromethoxy group imparts unique electronic properties, making it a sought-after intermediate for developing novel compounds with specific functionalities.
Pharmaceutical Intermediates
3-(Trifluoromethoxy)aniline is employed in the synthesis of active pharmaceutical ingredients (APIs). Its structure is incorporated into molecules designed to treat various medical conditions, leveraging the electron-withdrawing nature of the trifluoromethoxy group for modulated biological activity.
Agrochemical Development
This compound acts as a key intermediate in the production of pesticides, herbicides, and fungicides. The incorporation of the trifluoromethoxy motif can enhance the efficacy and metabolic stability of agrochemical products.
Material Science
The unique electronic and physical properties derived from the trifluoromethoxy group make 3-(Trifluoromethoxy)aniline useful in the research and development of advanced materials, potentially including polymers and specialty chemicals.
Organic Synthesis Building Block
As a versatile building block, it is used in a wide array of organic transformations. Researchers and chemists utilise it to introduce the 3-(trifluoromethoxy)phenyl moiety into complex molecular architectures.
| Molecular weight | 177.12 |
|---|---|
| Linear formula | CF3OC6H4NH2 |
| Assay | 98% |
| Boiling point | 72-73 °C/8 mmHg(lit.) |
| Density | 1.325 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.466(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 85 °C / 185 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-27-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Trifluoromethoxy)aniline used for?
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3-(Trifluoromethoxy)aniline (CAS: 1535-73-5) is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and advanced materials. Its unique trifluoromethoxy group provides specific electronic properties beneficial for these applications.
What are the CAS number and molecular formula for 3-(Trifluoromethoxy)aniline?
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The CAS number for 3-(Trifluoromethoxy)aniline is 1535-73-5, and its molecular formula is CF3OC6H4NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(Trifluoromethoxy)aniline with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-(Trifluoromethoxy)aniline be handled safely?
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Handling 3-(Trifluoromethoxy)aniline requires caution due to hazards including H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H332 (Harmful if inhaled), and H335 (May cause respiratory irritation). Always use appropriate personal protective equipment, such as eyeshields, face shields, gloves, and a suitable respirator, and handle in a well-ventilated area.
Is 3-(Trifluoromethoxy)aniline a controlled substance?
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The provided data does not indicate that 3-(Trifluoromethoxy)aniline (CAS: 1535-73-5) is a controlled substance.
How is 3-(Trifluoromethoxy)aniline packed and shipped?
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3-(Trifluoromethoxy)aniline is packed according to industry standards for chemical safety and export. It is shipped under UN classification NA 1993, PGIII, adhering to all relevant transport regulations.
How can I request a quote or sample for 3-(Trifluoromethoxy)aniline?
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To request a quote or sample for 3-(Trifluoromethoxy)aniline, please contact our sales department through the provided channels on the Tech Serve Solutions website.
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