3-(Trifluoromethoxy)benzoyl chloride

CAS 86270-03-3C8H4ClF3O2Chemical Synthesis

3-(Trifluoromethoxy)benzoyl chloride (CAS: 86270-03-3; Formula: C8H4ClF3O2; MW: 224.56) is a reactive organic compound, classified as an acid halide. It serves as a valuable building block in organic synthesis, primarily utilised in the preparation of more complex molecules. Its structure, featuring a trifluoromethoxy group and an acid chloride functionality, makes it a useful intermediate in the chemical and pharmaceutical industries for introducing specific structural motifs.

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3-(Trifluoromethoxy)benzoyl chloride (C8H4ClF3O2) — chemical structure, CAS 86270-03-3; Chemistry, fine chemical supplied by Tech Serve Solutions

Acid HalidesBuilding BlocksCarbonyl CompoundsChemical SynthesisOrganic Building Blocks

01 /Applications

Organic Synthesis Intermediate

Used as a key reagent in the synthesis of various organic compounds. The acid chloride group readily reacts with nucleophiles, allowing for the formation of esters, amides, and other derivatives.

Pharmaceutical Intermediate

Serves as a building block in the development and production of pharmaceutical agents. Its unique structural features can be incorporated into drug candidates to modulate their properties.

Material Science

Potentially employed in the synthesis of specialised polymers or functional materials where the trifluoromethoxybenzoyl moiety is desired for its electronic or physical properties.

02 /Properties

Molecular weight	224.56
Empirical formula	C8H4ClF3O2
Assay	98%
Density	1.419 g/mL at 25 °C

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Flash point	91 °C / 195.8 °F
Transport (UN / ADR)	UN 3265 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34-52/53
Safety statements (S)	26-36/37/39-45-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

86270-03-3

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-(Trifluoromethoxy)benzoyl chloride used for?

This compound is primarily used as an intermediate and building block in organic synthesis, including the preparation of pharmaceuticals and potentially in material science.

What are the CAS number and formula for this product?

The CAS number is 86270-03-3 and the empirical formula (Hill Notation) is C8H4ClF3O2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product with an assay of 98%. This is a technical or research grade, and it is not represented as USP, BP, EP, or any other pharmacopoeia standard.

How should 3-(Trifluoromethoxy)benzoyl chloride be handled safely?

This compound is classified as Danger, H314 (Causes severe skin burns and eye damage). Handle with extreme care using appropriate personal protective equipment, including gloves, eye protection, and protective clothing. Ensure adequate ventilation. Refer to the Safety Data Sheet for full handling instructions.

Is this product available for international export?

Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, including this product.