3-(Trifluoromethoxy)fluorobenzene
3-(Trifluoromethoxy)fluorobenzene (CAS: 1077-01-6, Formula: C7H4F4O) is a fluorinated aromatic compound supplied by Tech Serve Solutions. With a molecular weight of 180.10 g/mol, it serves as a valuable building block in organic synthesis. Its unique structure, featuring both trifluoromethoxy and fluoro substituents on a benzene ring, makes it useful for introducing specific functionalities into more complex molecules across various chemical research and development sectors.

Organic Synthesis Intermediate
This compound functions as a key intermediate in the synthesis of complex organic molecules. Its fluorinated nature can impart desirable properties such as increased metabolic stability or lipophilicity to target compounds.
Pharmaceutical Research
It is utilised in the development of novel pharmaceutical candidates. The trifluoromethoxy group is a common motif in medicinal chemistry, influencing drug potency and pharmacokinetic profiles.
Materials Science
3-(Trifluoromethoxy)fluorobenzene can be employed in the creation of advanced materials. Its fluorinated structure may contribute to specific electronic or physical properties in polymers or other advanced materials.
| Molecular weight | 180.10 |
|---|---|
| Empirical formula | C7H4F4O |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Trifluoromethoxy)fluorobenzene used for?
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3-(Trifluoromethoxy)fluorobenzene is used as a building block in organic synthesis, particularly in pharmaceutical research and potentially in materials science, to introduce fluorinated functionalities into target molecules.
What is the CAS number and formula for 3-(Trifluoromethoxy)fluorobenzene?
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The CAS number is 1077-01-6 and the molecular formula is C7H4F4O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. Purity and grade information are available upon request, and it is not represented as USP, BP, or EP grade.
How should 3-(Trifluoromethoxy)fluorobenzene be handled safely?
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Based on GHS classifications, it is a Warning substance (GHS07) that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, ensuring good ventilation and avoiding contact with skin, eyes, and clothing.
Is this chemical shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a quote or sample?
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To request a quote or sample of 3-(Trifluoromethoxy)fluorobenzene, please contact our sales team through the website or via the provided contact details.
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