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2-Bromopropionyl bromide

CAS 563-76-8CH3CHBrCOBrChemical Synthesis

2-Bromopropionyl bromide (CAS: 563-76-8) is a reactive organic compound with the linear formula CH3CHBrCOBr and a molecular weight of 215.87 g/mol. This acid halide serves as a valuable building block in organic synthesis. It is particularly useful for introducing the 2-bromopropionyl moiety in the preparation of various functionalised molecules, including polymers and heterocyclic compounds. Tech Serve Solutions supplies this chemical for research and development purposes.

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2-Bromopropionyl bromide (CH3CHBrCOBr) — chemical structure, CAS 563-76-8; Chemistry, fine chemical supplied by Tech Serve Solutions
Acid HalidesBuilding BlocksCarbonyl CompoundsChemical SynthesisOrganic Building Blocks
01 /Applications

Polymer Synthesis

Used as a macroinitiator in the synthesis of bromoester terminated polymers, such as poly(3-hexylthiophene), enabling further atom transfer radical polymerisation of acrylates.

Cellulose Modification

Employed in the direct acylation of cellulose within ionic liquids, such as 1-allyl-3-methylimidazolium chloride, to create cellulose macroinitiators.

Heterocyclic Chemistry

Applied in the synthesis of novel oxazolidone derivatives, specifically forming 3-(2-bromopropionyl)-2-oxazolidone structures for further chemical elaboration.

02 /Properties
Molecular weight215.87
Linear formulaCH3CHBrCOBr
Assay≥97.0% (AT)
Boiling point48-50 °C/10 mmHg(lit.)
Density2.03 g/mL at 20 °C2.061 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.518(lit.)n20/D 1.520
Vapour pressure1.3 mmHg (20 °C)
Vapour density7.5 (vs air)
Application2-Bromopropionyl bromide has been used in the synthesis of:• cellulose macroinitiator via direct acylation of cellulose in ionic liquid 1-allyl-3-methylimidazolium chloride1• 3-(2-bromopropionyl)-2-oxazolidone derivatives2• bromoester terminated poly(3-hexylthiophene), used as macroinitiator for atom transfer radical polymerization of acrylates3.
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H302Harmful if swallowed
  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point113 °C / 235.4 °F
Transport (UN / ADR)UN 3265 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)22-34
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
563-76-8
MDL number
MFCD00000142
PubChem substance
24855014
Beilstein registry
1071331
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Bromopropionyl bromide used for?

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2-Bromopropionyl bromide is used as a building block in organic synthesis, particularly for creating polymers and functionalised molecules via acylation reactions.

What is the CAS number and formula for 2-Bromopropionyl bromide?

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The CAS number is 563-76-8 and the linear formula is CH3CHBrCOBr.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-Bromopropionyl bromide with an assay of 97.0% (AT). This is a technical grade for laboratory and research use, and is not represented as USP, BP, or EP grade.

How should 2-Bromopropionyl bromide be handled safely?

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2-Bromopropionyl bromide is classified as Danger, causing severe skin burns and eye damage (H314) and is harmful if swallowed (H302). Handle with extreme care, using appropriate personal protective equipment including gloves, eye protection (faceshields/goggles), and respiratory protection. Ensure adequate ventilation. Consult the Safety Data Sheet (SDS) before use.

How is 2-Bromopropionyl bromide packed and shipped?

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2-Bromopropionyl bromide is packed and shipped according to UN 3265 regulations for corrosive liquid, acidic, organic, n.o.s., Packing Group II. TSS exports globally.

How can I request a quote or sample for 2-Bromopropionyl bromide?

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Please contact our sales team through the website or via email to request a quotation or a sample of 2-Bromopropionyl bromide.

Need 2-Bromopropionyl bromide in a specific grade or volume?