3-(Trifluoromethoxy)benzyl bromide
3-(Trifluoromethoxy)benzyl bromide (CAS: 159689-88-0; Formula: CF3OC6H4CH2Br; MW: 255.03) is a valuable organic building block featuring a benzyl bromide moiety and a trifluoromethoxy group. This compound serves as a key intermediate in organic synthesis, particularly for introducing the 3-(trifluoromethoxy)benzyl group into various molecular structures. Its applications are found in the development of pharmaceuticals, agrochemicals, and advanced materials.
Pharmaceutical Intermediate
This compound is utilised in the synthesis of novel pharmaceutical agents. The trifluoromethoxy group can enhance metabolic stability and lipophilicity, crucial properties for drug candidates.
Agrochemical Synthesis
It serves as a building block in the development of new agrochemicals. The fluorinated substituent can contribute to improved efficacy and environmental persistence profiles of pesticides and herbicides.
Materials Science
The compound finds application in the creation of advanced materials. It can be incorporated into polymers or organic electronic materials to impart specific chemical or physical properties.
Organic Synthesis
As a versatile reagent, it is employed in diverse organic transformations for constructing complex molecules. The reactive benzyl bromide functionality allows for facile nucleophilic substitution reactions.
| Molecular weight | 255.03 |
|---|---|
| Linear formula | CF3OC6H4CH2Br |
| Assay | 97% |
| Boiling point | 179 °C(lit.) |
| Density | 1.572 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.478(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 89 °C / 192.2 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Trifluoromethoxy)benzyl bromide used for?
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3-(Trifluoromethoxy)benzyl bromide is primarily used as a building block in organic synthesis for the preparation of pharmaceuticals, agrochemicals, and advanced materials. It is particularly useful for introducing the 3-(trifluoromethoxy)benzyl group into target molecules.
What is the CAS number and chemical formula for 3-(Trifluoromethoxy)benzyl bromide?
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The CAS number is 159689-88-0, and the chemical formula is CF3OC6H4CH2Br.
What grade and purity does Tech Serve Solutions supply for 3-(Trifluoromethoxy)benzyl bromide?
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Tech Serve Solutions supplies 3-(Trifluoromethoxy)benzyl bromide with a purity of 97% (assay). This product is suitable for research and chemical synthesis purposes. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should 3-(Trifluoromethoxy)benzyl bromide be handled safely?
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3-(Trifluoromethoxy)benzyl bromide is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including face shields, chemical-resistant gloves, goggles, and respiratory protection. Ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive handling instructions.
How is 3-(Trifluoromethoxy)benzyl bromide typically shipped?
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As a supplier and exporter of fine chemicals, Tech Serve Solutions packages and ships 3-(Trifluoromethoxy)benzyl bromide in compliance with all relevant national and international transport regulations for hazardous materials (UN 3265, Class 8, PG II).
How can I request a quote or sample for 3-(Trifluoromethoxy)benzyl bromide?
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To request a quote or a sample of 3-(Trifluoromethoxy)benzyl bromide, please visit the Tech Serve Solutions website or contact our sales department directly with your inquiry.
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