SB 228357
SB 228357 (CAS: 181629-93-6), with the empirical formula C22H17F4N3O2 and a molecular weight of 431.38 g/mol, is a white solid compound. It functions as an antagonist, particularly relevant in the study of serotonin receptor-mediated cell signalling. This compound is a valuable tool for researchers investigating cell biology, neuroscience, and neurotransmission, especially concerning serotonergic pathways.
- IUPAC
- N-[3-Fluoro-5-(3-pyridinyl)phenyl]-2,3-dihydro-5-methoxy-6-(trifluoromethyl)-1H-indole-1-carboxamide
Serotonin Receptor Research
SB 228357 is utilized in studies investigating the role of 5-HT2B and 5-HT2C serotonin receptors in cell signalling pathways. Its antagonistic properties allow researchers to probe the functions of these receptors in biological systems.
Neuroscience Investigations
As a bioactive small molecule, SB 228357 is employed in neuroscience research to understand neurotransmission and the complex mechanisms of the central nervous system. It aids in the study of serotonergic neurotransmitters.
Cell Biology Studies
This compound serves as a research tool in cell biology, providing a means to investigate cellular responses mediated by specific serotonin receptor subtypes. Its application aids in dissecting intricate cellular processes.
| Molecular weight | 431.38 |
|---|---|
| Empirical formula | C22H17F4N3O2 |
| Assay | ≥99% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: soluble ~8 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
| Application | SB-228357 may be used in 5-HT2B/2C serotonin receptor-mediated cell signaling studies. |
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Safety statements (S) | 22-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... HTR2B(3357), HTR2C(3358) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SB 228357 used for?
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SB 228357 is used as an antagonist in studies of 5-HT2B/2C serotonin receptor-mediated cell signalling, aiding research in neuroscience and cell biology.
What is the CAS number and formula for SB 228357?
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The CAS number for SB 228357 is 181629-93-6, and its empirical formula is C22H17F4N3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies SB 228357 with a purity of ≥99% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
How should SB 228357 be handled and stored?
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SB 228357 is a solid compound. Handle with appropriate personal protective equipment and store at 2-8°C. Refer to the Safety Data Sheet for comprehensive handling guidelines. According to WGK Germany, it is classified as hazard class 3.
How is SB 228357 shipped and exported?
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Tech Serve Solutions, a global supplier and exporter since 1998, ships and exports SB 228357 according to international regulations for chemical substances.
How can I request a sample or quote for SB 228357?
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To request a sample or quote for SB 228357, please contact our sales department through the TSS website or by phone.
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