SB 205384
SB 205384 (CAS: 160296-13-9), with the empirical formula C17H18N2O3S and a molecular weight of 330.40 g/mol, is an off-white solid chemical. It functions as an agonist and modulator for GABA and glycine receptors. This compound is primarily utilised in cell biology and neuroscience research to investigate cellular signalling pathways, neurotransmission, and ion channel activity, specifically focusing on GABA-gated currents.
- IUPAC
- 4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester

Neuroscience Research
SB 205384 is employed to investigate the mechanisms of neurotransmission and the function of GABA receptors in neuronal cells. Its use has been documented in studies of rat locus coeruleus neurons to understand GABA-gated currents.
Cell Signaling Studies
As a modulator of GABA and glycine receptors, SB 205384 is a valuable tool for studying cellular signalling pathways within the central nervous system. It aids in understanding the intricate communication between neurons.
Ion Channel Modulation Research
This compound serves as a ligand-gated ion channel modulator, enabling researchers to explore the complex electrophysiology of neuronal cells. Its specific action on GABAergic systems makes it useful for detailed ion channel characterisation.
| Molecular weight | 330.40 |
|---|---|
| Empirical formula | C17H18N2O3S |
| Form | solid |
| Colour | off-white |
| Solubility | DMSO: soluble18 mg/mLH2O: insoluble |
| Application | SB 205384 was used to study GABA-gated currents in rat locus coeruleus neurons.6 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SB 205384 used for?
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SB 205384 is used in neuroscience and cell biology research to study GABA-gated currents, cellular signalling, and neurotransmission, particularly as a GABA and glycine receptor modulator.
What are the CAS number and formula for SB 205384?
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The CAS number for SB 205384 is 160296-13-9 and its empirical formula is C17H18N2O3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies SB 205384 as a research-grade chemical. The specific assay is not detailed in the product data. TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling requirements for SB 205384?
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When handling SB 205384, appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used. The compound is classified with WGK Germany 3.
How is SB 205384 packed, shipped, and exported?
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SB 205384 is typically supplied as an off-white solid. Tech Serve Solutions exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to international shipping regulations for chemical compounds.
How can I request a sample or quote for SB 205384?
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To request a sample or a quote for SB 205384, please contact the Tech Serve Solutions sales team via the website or designated contact channels.
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