SAHA

CAS 149647-78-9C14H20N2O3Cell Biology

SAHA (CAS: 149647-78-9), with the empirical formula C14H20N2O3 and a molecular weight of 264.32 g/mol, is a significant research chemical. It functions as a potent inhibitor of histone deacetylases (HDACs). This action underpins its utility in investigating gene regulation, transcription processes, and cellular signalling pathways, making it a valuable tool in molecular biology and biochemical research.

IUPAC: N-hydroxy-N′-phenyl-octanediamide,Suberoylanilide hydroxamic acid,Vorinostat
Synonyms: Suberoylanilide hydroxamic acidVorinostat

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SAHA (C14H20N2O3) — chemical structure, CAS 149647-78-9; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCell BiologyS More...

01 /Applications

Gene Regulation Studies

SAHA is utilised to investigate the mechanisms of gene expression control. Its ability to inhibit histone deacetylases allows researchers to study the impact of histone acetylation on chromatin structure and gene accessibility.

Cellular Signalling Research

This compound serves as a tool for exploring cellular signalling cascades. Researchers employ SAHA to understand how HDAC inhibition influences various intracellular communication pathways and cellular responses.

Transcription Regulation Analysis

SAHA aids in studying the regulation of transcription. By modulating histone acetylation, it provides insights into the enzymes and processes that govern the initiation and elongation of RNA synthesis.

02 /Properties

Molecular weight	264.32
Empirical formula	C14H20N2O3
Assay	≥98% (HPLC)
Form	powder
Colour	white to tan
Solubility	DMSO: ≥15 mg/mL
Storage temperature	−20°C
Application	SAHA may be used to study gene regulation, transcription regulation and cell signaling.

03 /Safety & handling

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Danger

Hazard statements

H341Suspected of causing genetic defects
H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use
P281Use personal protective equipment as required
P308IF exposed or concerned

Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	61-68
Safety statements (S)	53-36/37-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

149647-78-9

05 /Additional specifications

Shipped In	wet ice

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is SAHA used for?

SAHA is used in research to study gene regulation, transcription regulation, and cell signalling, primarily as an inhibitor of histone deacetylases.

What is the CAS number and formula for SAHA?

The CAS number for SAHA is 149647-78-9, and its empirical formula is C14H20N2O3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies SAHA with a minimum purity of ≥98% (HPLC). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmaceutical grade.

How should SAHA be handled and stored?

SAHA is classified as Danger (GHS08) with hazard statements H341 (Suspected of causing genetic defects) and H360 (May damage fertility or the unborn child). It should be handled with extreme caution in a well-ventilated area, using appropriate personal protective equipment. Store at -20°C.