S(−)-Willardiine
S(−)-Willardiine (CAS: 21416-43-3), with the molecular formula C7H9N3O4 and a molecular weight of 199.16 g/mol, is a white solid. This compound serves as a selective agonist for AMPA and kainate subtypes of ionotropic glutamate receptors. It is a valuable research tool in neuroscience, aiding the study of excitatory amino acid neurotransmission and its role in neuronal signaling pathways. S(−)-Willardiine is primarily used in biochemical and pharmacological research.
- IUPAC
- S(−)-α-Amino--3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid
Neuroscience Research
S(−)-Willardiine acts as a potent agonist for AMPA and kainate receptors, making it indispensable for investigating excitatory neurotransmission in the central nervous system. Researchers utilise it to explore neuronal excitability and synaptic plasticity.
Cellular Signaling Studies
This compound is employed to study the downstream effects of glutamate receptor activation in cellular models. It helps elucidate signalling cascades involved in neuronal function and dysfunction.
Pharmacological Tool
As a well-characterised receptor modulator, S(−)-Willardiine is used in drug discovery programmes targeting neurological disorders. It aids in the screening and validation of potential therapeutic agents.
| Molecular weight | 199.16 |
|---|---|
| Empirical formula | C7H9N3O4 |
| Form | solid |
| Colour | white |
| Solubility | 0.1 M NaOH: soluble7.2 mg/mLDMSO: insolubleH2O: insolubleethanol: insoluble |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is S(−)-Willardiine used for?
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S(−)-Willardiine is primarily used in neuroscience research as a selective agonist for AMPA and kainate receptors to study excitatory neurotransmission and neuronal signaling.
What is the CAS number and molecular formula for S(−)-Willardiine?
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The CAS number for S(−)-Willardiine is 21416-43-3, and its molecular formula is C7H9N3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies S(−)-Willardiine as a research-grade chemical. Specific purity assays are available on the Certificate of Analysis for each batch. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should S(−)-Willardiine be handled safely?
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When handling S(−)-Willardiine, it is essential to wear appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, due to its classification with WGK Germany 3.
How is S(−)-Willardiine packed, shipped, and exported?
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S(−)-Willardiine is carefully packed in compliance with international shipping regulations. Tech Serve Solutions, a specialist global supplier and exporter since 1998, ensures secure and compliant handling for worldwide export.
How can I request a sample or quote for S(−)-Willardiine?
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To request a sample or quote for S(−)-Willardiine, please contact our sales team through the website or by phone. Provide the product name and CAS number for prompt service.
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