S(−)-Verapamil hydrochloride hydrate
S(−)-Verapamil hydrochloride hydrate (CAS 36622-28-3) is a chiral compound with the molecular formula C27H38N2O4 · HCl · xH2O. Available as a white to beige powder with a molecular weight of 491.06 on an anhydrous basis, it is soluble in water and ethanol. This chemical is recognised for its role in biological research, particularly in studies involving ion channels and cellular signaling pathways. TSS supplies this compound with an assay of ≥98%.
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Calcium Channel Modulation Research
S(−)-Verapamil hydrochloride hydrate serves as a valuable tool in research exploring the function and regulation of voltage-gated calcium channels. Its specific interactions with these channels aid in understanding cellular electrophysiology and signal transduction.
Cell Biology Studies
This compound is utilized in cell biology to investigate cellular processes affected by ion channel activity. Its application helps researchers elucidate mechanisms related to cell signaling, proliferation, and apoptosis.
Neuroscience Investigations
In neuroscience, S(−)-Verapamil hydrochloride hydrate is employed to study neuronal function and neurotransmission, particularly where calcium influx plays a critical role. It aids in understanding conditions influenced by ion channel dysregulation.
| Molecular weight | 491.06 (anhydrous basis) |
|---|---|
| Empirical formula | C27H38N2O4 · HCl · xH2O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | H2O: >30 mg/mLethanol: soluble |
| Optical activity | [α]22/D −6.1°, c = 0.1 in ethanol(lit.) |

Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccatedprotect from light |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is S(−)-Verapamil hydrochloride hydrate used for?
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S(−)-Verapamil hydrochloride hydrate is primarily used in research for studying calcium channel modulation, cell biology, and neuroscience, particularly investigating cellular electrophysiology and signal transduction pathways.
What is the CAS number and formula for S(−)-Verapamil hydrochloride hydrate?
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The CAS number for the anhydrous form is 36622-28-3, and the empirical formula is C27H38N2O4 · HCl · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies S(−)-Verapamil hydrochloride hydrate with an assay of ≥98% (HPLC). This product is intended for research and laboratory use; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should S(−)-Verapamil hydrochloride hydrate be handled?
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S(−)-Verapamil hydrochloride hydrate is classified as toxic if swallowed (H301) and requires careful handling. Personnel should use appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirator cartridges. Store desiccated and protect from light.
How is this chemical packed and shipped?
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This product is packed in accordance with safety regulations for hazardous materials and is exported globally by TSS. It is classified under UN 2811, 6.1, PGIII for transport.
How can I request a sample or quote for S(−)-Verapamil hydrochloride hydrate?
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To request a sample or a quotation, please contact the TSS sales team through our website or by phone, providing the product name and CAS number (36622-28-3).
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