S(−)-Baclofen hydrochloride
S(−)-Baclofen hydrochloride (CAS: 63701-56-4) is a chemical compound with a molecular weight of 250.12 g/mol. It is presented as a white solid. As a GABAergic agent, it is primarily utilised in research settings to investigate neurological pathways and neurotransmission. Its specific stereochemistry, indicated by the S(−) designation, is crucial for its biological activity in experimental studies.
- IUPAC
- S(–)-β-(Aminomethyl)-4-chlorobenzenepropanoic acid hydrochloride

Neuroscience Research
Utilised in studies investigating the role of GABAergic systems in the central nervous system. It serves as a tool to modulate neuronal activity and explore neurotransmitter functions in various experimental models.
Pharmacological Tool
Employed as a selective GABA-B receptor agonist in biochemical and physiological research. It aids in understanding receptor binding, signalling pathways, and potential therapeutic targets within neuroscience.
Cell Biology Studies
Applied in cell-based assays to examine the effects of GABA-B receptor modulation on cellular functions and signalling cascades, particularly within neuronal cell cultures.
| Molecular weight | 250.12 |
|---|---|
| Empirical formula | C10H12ClNO2 · HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: >20 mg/mL |
| Optical activity | [α]28/D −2.2°, c = 0.9 in methanol(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is S(−)-Baclofen hydrochloride used for?
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S(−)-Baclofen hydrochloride (CAS: 63701-56-4) is primarily used in research settings, particularly within neuroscience, to study GABAergic systems, neurotransmission, and GABA-B receptor activity.
What is the CAS number and empirical formula for S(−)-Baclofen hydrochloride?
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The CAS number is 63701-56-4, and the empirical formula is C10H12ClNO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies S(−)-Baclofen hydrochloride with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How is S(−)-Baclofen hydrochloride handled and stored?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It is shipped according to UN 2811 6.1 / PGIII regulations, with a WGK Germany rating of 3.
Can I request a sample or quote for S(−)-Baclofen hydrochloride?
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Yes, you can request a sample or a quote for S(−)-Baclofen hydrochloride by contacting our sales team through the website or by phone.
Is S(−)-Baclofen hydrochloride a controlled substance?
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The provided data does not indicate that S(−)-Baclofen hydrochloride is a controlled substance. However, users should always comply with local regulations.
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