Desipramine hydrochloride
Desipramine hydrochloride (CAS 58-28-6), a tricyclic antidepressant, is primarily used in research settings to investigate its effects on neurotransmitter reuptake. Its molecular formula is C18H22N2 · HCl, with a molecular weight of 302.84 g/mol. This white to off-white powder is soluble in water and is valuable for studies in neuroscience, cell signaling, and pharmacology, serving as a tool to understand biogenic amine transport mechanisms. It is supplied by TSS with an assay of ≥98% (TLC).
Neurotransmitter Reuptake Inhibition Studies
Desipramine hydrochloride is utilised in pharmacological research to examine its potent inhibition of norepinephrine reuptake. This allows scientists to study the role of noradrenergic pathways in various physiological and pathological processes.
Neuroscience Research Tool
As a selective norepinephrine reuptake inhibitor, it serves as a valuable tool for investigating neurotransmission and its modulation within the central nervous system. Its use aids in understanding complex neural circuits and neurochemical imbalances.
Cellular Signaling and Pathway Analysis
Researchers employ desipramine hydrochloride to probe cellular signaling pathways, particularly those influenced by monoamine transporters. This helps in elucidating the mechanisms underlying neuronal function and dysfunction.
Biochemical Assays
The compound is used in biochemical assays to quantify transporter activity or to serve as a reference standard in the development of new therapeutic agents targeting monoamine systems.
| Molecular weight | 302.84 |
|---|---|
| Empirical formula | C18H22N2 · HCl |
| Assay | ≥98% (TLC) |
| Form | powder |
| Colour | white to off-white |
| Solubility | H2O: soluble50 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-42/43 |
| Safety statements (S) | 22-24-26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Desipramine hydrochloride used for?
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Desipramine hydrochloride is primarily used in research settings, particularly in neuroscience and pharmacology, to study neurotransmitter reuptake mechanisms, specifically the inhibition of norepinephrine reuptake. It is a valuable tool for investigating cellular signaling and neurotransmission.
What is the CAS number and formula for Desipramine hydrochloride?
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The CAS number for Desipramine hydrochloride is 58-28-6, and its molecular formula is C18H22N2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Desipramine hydrochloride with an assay of ≥98% determined by TLC. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Desipramine hydrochloride be handled safely?
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When handling Desipramine hydrochloride, it is essential to wear appropriate personal protective equipment, including a dust mask (type N95), eyeshields, face shield, and gloves. Ensure adequate ventilation and avoid breathing dust. Refer to the safety data sheet for comprehensive handling instructions.
Is Desipramine hydrochloride a controlled substance?
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The provided data does not indicate that Desipramine hydrochloride is a controlled substance. However, users should always verify local regulations.
How is Desipramine hydrochloride packed, shipped, and exported?
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Desipramine hydrochloride is typically supplied as a white to off-white powder. Specific packing, shipping, and export details can be provided upon request, adhering to all relevant international shipping regulations.
How can I request a sample or quote for Desipramine hydrochloride?
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To request a sample or quote for Desipramine hydrochloride, please contact our sales team via the website or direct email, specifying the quantity and delivery location.
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