Deoxycholic acid
Deoxycholic acid (CAS 83-44-3), with the molecular formula C24H40O4 and a molecular weight of 392.57 g/mol, is an anionic detergent and a secondary bile acid. It plays a role in the emulsification and absorption of dietary fats. Deoxycholic acid is utilized in various research applications, including studies on intestinal barrier function and bile formation, and as a biochemical reagent.
- IUPAC
- 3α,12α-Dihydroxy-5β-cholanic acid,7-Deoxycholic acid,Desoxycholic acid
- Synonyms
- 3α,12α-Dihydroxy-5β-cholanic acid7-Deoxycholic acidDesoxycholic acid
Intestinal Barrier Function Research
Deoxycholic acid has been employed in scientific studies to investigate the impact of varying bile acid concentrations on the integrity and function of the intestinal barrier in animal models.
Bile Formation Studies
This compound serves as a tool in research to characterise bile acid metabolism and secretion, particularly in models of hepatic disruption.
Biochemical Reagent
As a bile acid derivative and detergent, deoxycholic acid is used in biochemical research and as a component in certain biological assays.
| Molecular weight | 392.57 |
|---|---|
| Empirical formula | C24H40O4 |
| Assay | ≥98% (HPLC) |
| Impurities tested | ≤0.005% Phosphorus (P)≤0.1% Insoluble matter |
| Application | Deoxycholic acid has been used in a study to assess how physiological concentrations of ursodeoxycholic acid (UDCA) vs. deoxycholic acid (DCA) affect barrier function in mouse intestinal tissue. 1 It has also been used in a study to characterize bile formation in a mouse model with hepatic disruption of the cytochrome p450 (CYP) oxidoreductase gene. 2 |
| Melting point | 171-174 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
| Cation traces | Al: ≤0.001%Ca: ≤0.01%Cu: ≤0.0005%Fe: ≤0.005%K: ≤0.005%Mg: ≤0.005%NH4+: ≤0.05%Na: ≤0.02%Pb: ≤0.001%Zn: ≤0.0005% |
| Ignition residue | ≤0.1% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | anionic |
|---|---|
| Product Line | BioXtra |
| Mol Wt | average mol wt 1200-5000 |
| Gene Information | human ... ATIC(471) |
| Aggregation Number | 3-12 |
| Cmc | 2-6 |
| Hlb | 16 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Deoxycholic acid (CAS 83-44-3) used for?
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Deoxycholic acid is used in biochemical research for applications such as studying intestinal barrier function, characterising bile formation, and as an anionic detergent.
What is the CAS number and molecular formula for Deoxycholic acid?
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The CAS number for Deoxycholic acid is 83-44-3, and its molecular formula is C24H40O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Deoxycholic acid with a purity of ≥98% (HPLC). This product is not represented as USP, BP, EP, or other pharmacopoeia grade.
What are the primary safety concerns when handling Deoxycholic acid?
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Deoxycholic acid is classified with a GHS07 symbol and a 'Warning' signal word. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used.
Does Tech Serve Solutions export Deoxycholic acid?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Deoxycholic acid.
How can I request a quote or sample for Deoxycholic acid?
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To request a quote or sample for Deoxycholic acid, please contact our sales team through the website or by phone.
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