S(−)-Terguride hydrogen maleate
S(−)-Terguride hydrogen maleate (CAS: 37686-85-4) is a white solid compound with the molecular formula C20H28N4O · C4H4O4 and a molecular weight of 456.53. It is a dopaminergic agent used in neuroscientific research. This compound exhibits solubility in methanol and limited solubility in water. Terguride has been utilised in studies investigating its effects on drug dependence models, specifically concerning naloxone-precipitated place aversion in morphine-dependent rats.
- IUPAC
- S(–)-N,N-Diethyl-N′-[(8a)-6-methylergolin-8-yl]urea
Neuroscience Research
S(−)-Terguride hydrogen maleate serves as a valuable tool in neuroscience for investigating dopaminergic pathways and neurotransmission. Its specific effects on receptor systems make it useful for understanding neurological processes.
Drug Dependence Studies
The compound has been employed in preclinical research to evaluate its influence on conditioned place aversion in animal models of opioid dependence. These studies help elucidate mechanisms related to addiction and withdrawal.
Cell Biology and Signaling
As a dopaminergic agent, Terguride can be used to explore cellular responses and signaling pathways mediated by dopamine receptors in various biological systems.
| Molecular weight | 456.53 |
|---|---|
| Empirical formula | C20H28N4O · C4H4O4 |
| Form | solid |
| Colour | white |
| Solubility | H2O: slightly soluble1.26 mg/mLmethanol: soluble14 mg/mL |
| Optical activity | [α]20/D −14°, c = 0.1 in H2O(lit.) |
| Application | Terguride has been used to evaluate its effect on naloxone-precipitated place aversion in morphine-dependent rats1. |
Hazard statements
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 62 |
| Safety statements (S) | 53-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is S(−)-Terguride hydrogen maleate used for?
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S(−)-Terguride hydrogen maleate is used in scientific research, particularly in neuroscience, to study dopaminergic systems, neurotransmission, and drug dependence models, such as naloxone-precipitated place aversion in morphine-dependent rats.
What is the CAS number and chemical formula for S(−)-Terguride hydrogen maleate?
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The CAS number for S(−)-Terguride hydrogen maleate is 37686-85-4, and its chemical formula is C20H28N4O · C4H4O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies S(−)-Terguride hydrogen maleate as a research-grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade. Purity information can be found on the product's Certificate of Analysis.
How should S(−)-Terguride hydrogen maleate be handled?
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S(−)-Terguride hydrogen maleate is classified as a health hazard (H361) and requires careful handling. It is advised to wear appropriate personal protective equipment, including eyeshields and gloves, and use a suitable respirator. Always consult the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.
Is S(−)-Terguride hydrogen maleate a controlled substance?
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Based on the provided data, there is no indication that S(−)-Terguride hydrogen maleate is a scheduled or controlled substance.
How is S(−)-Terguride hydrogen maleate shipped?
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Tech Serve Solutions exports fine chemicals globally, adhering to all relevant shipping and regulatory requirements for the safe transport of chemical compounds.
How can I request a quote or sample for S(−)-Terguride hydrogen maleate?
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To request a quote or a sample of S(−)-Terguride hydrogen maleate, please contact our sales team through the TSS website or by using the provided contact details.
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