Folinic acid calcium salt hydrate
Folinic acid calcium salt hydrate (CAS 1492-18-8 (anhydrous)), molecular formula C20H21CaN7O7 · xH2O, is a high-purity chemical supplied by Tech Serve Solutions for cell biology applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- 5-Formyl-5,6,7,8-tetrahydrofolic acid calcium salt,5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid calcium salt,5-HCO-H4PteGlu,Calcium folinate,Citrovorum factor calcium salt,Leucovorin calcium salt
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| Molecular weight | 511.50 (anhydrous basis) |
|---|---|
| Empirical formula | C20H21CaN7O7 · xH2O |
| Application | Calcium folinate offsets the effects of folic acid antagonists that act by binding dihydrofolate reductase and blocking the conversion of folic acid to tetrahydrofolate. In medicine, calcium folinate is used after treatment with methotrexate to reduce the toxicity of the methotrexate. Calcium folinate is also used to enhance the cytotoxic effect of 5-fluorouracil in the treatment of cancer. |
Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38-42/43 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Folinic acid calcium salt hydrate?
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Folinic acid calcium salt hydrate (CAS 1492-18-8 (anhydrous)), molecular formula C20H21CaN7O7 · xH2O, is a high-purity chemical supplied by Tech Serve Solutions for cell biology applications, to USP, BP and EP standards.
What grades of Folinic acid calcium salt hydrate does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Folinic acid calcium salt hydrate in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of Folinic acid calcium salt hydrate?
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Folinic acid calcium salt hydrate has CAS number 1492-18-8 (anhydrous) and molecular formula C20H21CaN7O7 · xH2O. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for Folinic acid calcium salt hydrate?
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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
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Yes. Every batch of Folinic acid calcium salt hydrate ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should Folinic acid calcium salt hydrate be stored?
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Store Folinic acid calcium salt hydrate in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is Folinic acid calcium salt hydrate used for?
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Folinic acid calcium salt hydrate is used in cell biology applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for Folinic acid calcium salt hydrate?
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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
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