S-(5′-Adenosyl)-L-homocysteine
S-(5′-Adenosyl)-L-homocysteine (CAS: 979-92-0, Formula: C14H20N6O5S, MW: 384.41) is a vital biochemical compound involved in intracellular homocysteine stress. As a key player in epigenetic regulation, it acts as a competitive inhibitor of DNA methyltransferases. This Premium grade crystalline material is primarily used in research settings to study epigenetics, particularly in hyperhomocysteinemic conditions and related metabolic pathways.
- IUPAC
- 5′-Deoxy-S-adenosyl-L-homocysteine,AdoHcy,S-(5′-Deoxyadenosine-5′)-L-homocysteine
- Synonyms
- 5′-Deoxy-S-adenosyl-L-homocysteineAdoHcyS-(5′-Deoxyadenosine-5′)-L-homocysteine
Epigenetic Research
S-(5′-Adenosyl)-L-homocysteine serves as a crucial tool in epigenetic research, functioning as a competitive inhibitor of S-adenosyl-L-methionine-dependent methyltransferases. It is instrumental in studying the role of DNA methylation in various biological processes and disease states.
Metabolic Pathway Studies
This compound is utilized in the investigation of cellular metabolism, particularly focusing on homocysteine pathways and the activity of enzymes like S-adenosylhomocysteine hydrolase (AHCY). Understanding these pathways is critical for comprehending cellular homeostasis.
Cell Biology Investigations
As a bioactive small molecule, S-(5′-Adenosyl)-L-homocysteine is employed in cell biology research to explore the effects of intracellular homocysteine levels and methylation status on cellular function and gene expression.
| Molecular weight | 384.41 |
|---|---|
| Empirical formula | C14H20N6O5S |
| Form | crystalline |
| Storage temperature | −20°C |
| Application | S-(5′-Adenosyl)-L-homocysteine (AdoHcy) is a component of intracellular homocysteine stress. AdoHcy is a competitive inhibitor (versus AdoMet) of DNA methyltransferases (S-adenosyl-L-methionine (AdoMet)-dependent methyltransferases) involved in epigenetics; consequently AdoHcy is used in a variety of studies on epigenetics in hyperhomocysteinemic states. S-adenosylhomocysteine (AdoHcy) is metabolized by S-adenosylhomocysteine (AdoHcy) hydrolase (AHCY). |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | PREMIUM |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is S-(5′-Adenosyl)-L-homocysteine used for?
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S-(5′-Adenosyl)-L-homocysteine is used in research for studying epigenetics, particularly DNA methylation and hyperhomocysteinemic states, as well as for investigating metabolic pathways and cellular biology.
What is the CAS number and formula for S-(5′-Adenosyl)-L-homocysteine?
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The CAS number for S-(5′-Adenosyl)-L-homocysteine is 979-92-0, and its empirical formula is C14H20N6O5S.
What grade and purity does Tech Serve Solutions supply for S-(5′-Adenosyl)-L-homocysteine?
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Tech Serve Solutions supplies S-(5′-Adenosyl)-L-homocysteine in a PREMIUM crystalline grade. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial standards. Purity details are available on the Certificate of Analysis.
How should S-(5′-Adenosyl)-L-homocysteine be handled safely?
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When handling S-(5′-Adenosyl)-L-homocysteine, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. The compound is classified under WGK Germany 3, indicating a high hazard to water.
How is S-(5′-Adenosyl)-L-homocysteine packed, shipped, and exported?
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S-(5′-Adenosyl)-L-homocysteine is carefully packed to maintain its stability during transport. We offer global export services for research and development purposes. Specific packaging and shipping details can be provided upon request.
How can I request a sample or quote for S-(5′-Adenosyl)-L-homocysteine?
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To request a sample or a quotation for S-(5′-Adenosyl)-L-homocysteine, please contact our sales team through the website or by phone, providing your specific requirements.
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