Dichloro(1,5-cyclooctadiene)palladium(II)
Dichloro(1,5-cyclooctadiene)palladium(II) (CAS: 12107-56-1), with the empirical formula C8H12Cl2Pd and a molecular weight of 285.51 g/mol, is a palladium complex widely employed as a catalyst. It is particularly valued for its efficacy in catalysing the formation of carbon-carbon and carbon-nitrogen bonds. Its applications span various organic transformations essential in synthetic chemistry, making it a key reagent for researchers and industrial chemists.
- IUPAC
- PdCl2(cod)
- Synonyms
- C8H12Cl2PdPdCl2(cod)Dichloro(1,5-cyclooctadiene)palladium(1,5-Cyclooctadiene)dichloropalladium(II)

C-C Bond Formation
This palladium complex serves as an effective catalyst for forming carbon-carbon bonds. It is instrumental in reactions such as the Heck coupling of alkynes with alkenes and the Suzuki cross-coupling of aryl bromides.
C-N Bond Formation
The compound facilitates the formation of carbon-nitrogen bonds, a crucial step in synthesising many organic molecules. It is used in the allylic substitution of oximes with allylic acetate for this purpose.
Methoxycarbonylation Reactions
Dichloro(1,5-cyclooctadiene)palladium(II) is utilised in methoxycarbonylation reactions. An example includes the methoxycarbonylation of iodobenzene, enabling the introduction of a methoxycarbonyl group.
| Molecular weight | 285.51 |
|---|---|
| Empirical formula | C8H12Cl2Pd |
| Assay | 99% |
| Application | Catalyst for C-C bond and C-N formation, used in Heck coupling of alkynes with alkenes , Suzuki cross-coupling of aryl bromides , allylic substitution of oximes with allylic acetate , and methoxycarbonylation of iodobenzene. |
| Melting point | 210 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dichloro(1,5-cyclooctadiene)palladium(II) used for?
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Dichloro(1,5-cyclooctadiene)palladium(II) is primarily used as a catalyst for forming carbon-carbon and carbon-nitrogen bonds in organic synthesis. Key applications include Heck coupling, Suzuki cross-coupling, and methoxycarbonylation reactions.
What is the CAS number and formula for Dichloro(1,5-cyclooctadiene)palladium(II)?
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The CAS number for Dichloro(1,5-cyclooctadiene)palladium(II) is 12107-56-1, and its empirical formula is C8H12Cl2Pd.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dichloro(1,5-cyclooctadiene)palladium(II) with a purity of 99%. This product is supplied as a research or technical grade chemical, and TSS does not represent it as USP, BP, or EP grade.
What are the safety precautions for handling this chemical?
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This compound is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It is recommended to use a dust mask type N95 (US), wear eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. Follow all precautionary statements, including P261 and P305 + P351 + P338.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions packs and ships this chemical with appropriate safety measures. We are experienced in global export, ensuring compliance with all relevant shipping regulations for hazardous materials.
How can I request a quote or sample?
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To request a quote or a sample, please visit the product page on our website and use the 'Request a Quote' or 'Request a Sample' form, or contact our sales team directly.
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